Results 81 to 90 of about 6,094,300 (289)

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Impact of positive surgical margin location and perineural invasion on biochemical recurrence in patients undergoing radical prostatectomy

World Journal of Surgical Oncology, 2020
Objective To estimate the prognostic value of positive surgical margins (PSM) location and perineural invasion (PNI) for biochemical recurrence (BCR) in patients undergoing radical prostatectomy (RP).
Zhenpeng Lian, Hongtuan Zhang, Zhaowei He, Shenfei Ma, Xiaoming Wang, Ranlu Liu   +5 more
doaj   +1 more source

Histologically positive esophageal margin in the surgical treatment of gastric cancer

The American Journal of Surgery, 1980
Histologically positive esophageal margins caused by transection of the esophagus in an area involved by disease were encountered in 20 percent of 350 patients undergoing total or proximal subtotal gastrectomy for gastric cancer. There was a significant increase in the incidence of positive margins in patients with neoplasms of the cardia and in those ...
Papachristou, D. N., Agnanti, N., D'Agostino, H., Fortner, J. G.   +3 more
openaire   +3 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Analysis of risk factors for positive margins in robot-assisted laparoscopic radical prostatectomy with Retzius-sparing (RS-RARP)

World Journal of Surgical Oncology
Objective This study aims to analyze the risk factors for positive surgical margins following robot-assisted laparoscopic radical prostatectomy with Retzius-sparing (RS-RARP) to provide a basis for clinical preoperative evaluation and intraoperative ...
Hua Yang, Bo Wu, Xuchang Liu, Kaiyuan Jia, Junyuan Bing, Yangjie Gao, Pengliang Shen, Xiaoming Cao   +7 more
doaj   +1 more source

P53-positive expression in dysplastic surgical margins is a predictor of tumor recurrence in patients with early oral squamous cell carcinoma

, 2019
Xi-Hu Yang,1,* Liang Ding,2,* Yong Fu,1 Sheng Chen,3 Lei Zhang,3 Xiao-Xin Zhang,2 Xiao-Feng Huang,3 Zhan-Yi Lu,1 Yan-Hong Ni,2 Qin-Gang Hu1 1Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing ...
Huang XF, Yang XH, Zhang XX, Lu ZY, Hu QG, Fu Y, Zhang L, Chen S, Ding L, Ni YH   +9 more
core  

High-Volume Surgeons Deliver Larger Surgical Margins in Oral Cavity Cancer

, 2016
Purpose In oral cavity cancer surgery there are many factors that contribute to the surgical margin; thus, the factors determining patient outcomes are still not completely understood.
Batstone, MD, Ellis, OG, David, MC, Park, DJ   +3 more
core   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Tenosynovial Giant Cell Tumors of the Hand: Analysis of Risk Factors for Surgical Margin and Recurrence

Medicina
Background and Objective: Tenosynovial giant cell tumors (TGCTs) are benign but potentially aggressive soft-tissue tumors, most commonly affecting the hand and frequently associated with local recurrence despite surgical treatment.
Tolgahan Cengiz, Şafak Aydın Şimşek, Ercan Bayar, Furkan Erdoğan, Alparslan Yurtbay, Hüseyin Sina Coşkun, Ahmet Pişkin, Nevzat Dabak   +7 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source