Results 181 to 190 of about 1,944,556 (307)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Positive symptoms and their associations with life and trauma events among young adults in a first-episode psychosis clinic: qualitative analysis. [PDF]

BJPsych Open
Ternamian AA, Marchal M, Haesebaert J, Haesebaert F.   +3 more
europepmc   +1 more source

Dissociation as a causal pathway from sexual abuse to positive symptoms in the spectrum of psychotic disorders. [PDF]

BMC Psychiatry, 2021
Khosravi M, Bakhshani NM, Kamangar N.
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Disentangling negative and positive symptoms in schizophrenia and autism spectrum disorder. [PDF]

Schizophr Res
Corbera S, Wexler BE, Bell MD, Pittman B, Pelphrey K, Pearlson G, Assaf M.   +6 more
europepmc   +1 more source

Positive Symptoms in Antipsychotic-naïve Schizophrenia are Associated with Increased Body Mass Index after Treatment. [PDF]

Clin Psychopharmacol Neurosci, 2021
Lin SH, Tseng HH, Tsai HC, Chi MH, Lee IH, Chen PS, Chen KC, Yang YK.   +7 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Environmental Adversity Is Associated With Attenuated Positive Symptoms and Complex Cognition in a Long-term Follow-up of the Philadelphia Neurodevelopmental Cohort. [PDF]

Schizophr Bull
Ered A, Dietterich TE, Shahriar SS, Wong TY, Moore TM, Ruparel K, Barzilay R, Taylor JH, Calkins ME, Gur RC, Gur RE.   +10 more
europepmc   +1 more source

Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS

, 2023
Woods SW, Parker S, Kerr MJ, Walsh BC, Wijtenburg SA, Prunier N, Nunez AR, Buccilli K, Mourgues-Codern C, Brummitt K, Kinney KS, Trankler C, Szacilo J, Colton B, Ali M, Haidar A, Billah T, Huynh K, Ahmed U, Adery LL, Corcoran CM, Perkins DO, Schiffman J, Perez J, Mamah D, Ellman LM, Powers AR, Coleman MJ, Anticevic A, Fusar-Poli P, Kane JM, Kahn RS, McGorry PD, Bearden CE, Shenton ME, Nelson B, Calkins ME, Hendricks L, Bouix S, Addington J, McGlashan TH, Yung AR, the Accelerating Medicines Partnership Schizophrenia, AMP SCZ Working Group and Subgroup leaders (not previously listed):, Allott K, Clark SR, Kapur T, Lavoie S, Lewandowski KE, Mathalon DH, Pasternak O, Stone WS, Torous J, National Institute of Mental Health Project Scientists:, Rowland LM, Zhan M, Research Network and DPACC Investigators (not previously listed):, Amminger P, Arango C, Broome MR, Cadenhead KS, Chen EY, Choi J, Kevin Cho KI, Conus P, Cornblatt BA, Glenthøj LB, Horton LE, Kambeitz J, Keshavan MS, Koutsouleris N, Langbein K, Diaz-Caneja CM, Mittal VA, Nordentoft M, Gaspar Ramos PA, Pearlson GD, Shah JL, Smesny S, Strauss GP, Wang J, Study Coordinators and Project Managers (not previously listed):, Marcy PJ, Matneja P, Phassouliotis C, Ray S, Snowball C, Spark J, Tod S, Individual names of AMP SCZ collaborators are listed in the Acknowledgment.   +89 more
europepmc   +1 more source

Reduced TMS-evoked fast oscillations in the motor cortex predict the severity of positive symptoms in first-episode psychosis. [PDF]

Prog Neuropsychopharmacol Biol Psychiatry, 2021
Donati FL, Kaskie R, Reis CC, D'Agostino A, Casali AG, Ferrarelli F.   +5 more
europepmc   +1 more source