Results 151 to 160 of about 167,379 (299)

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

open access: yesAdvanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang   +5 more
wiley   +1 more source

The 5Cs of Positive Youth Development and Risk Behaviors in a Sample of Spanish Emerging Adults: A Partial Mediation Analysis of Gender Differences. [PDF]

open access: yesEur J Investig Health Psychol Educ, 2023
Gomez-Baya D   +5 more
europepmc   +1 more source

Designing Ductile 2‐GPa Yielding Titanium Alloys via Multifunctional Subgrain Boundaries and Nanoprecipitates

open access: yesAdvanced Science, EarlyView.
By engineering ultrafine β‐subgrains and nanoscale α‐precipitates in titanium alloys, the unique architecture achieves an unprecedented ultra‐high strength of 2 GPa while maintaining a notable uniform elongation of 6%, a combination that is both rare and highly promising for structural applications of titanium alloys.
Dingxuan Zhao   +10 more
wiley   +1 more source

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu   +10 more
wiley   +1 more source

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