Results 101 to 110 of about 153,438 (339)
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
An Interactionist View on the Relation between Law and Morality [PDF]
Introduction The claim of this book is that many issues may be put into a new light if we analyse them with explicit attention to the role of ideals. The relation between law and morality is one of these themes; indeed, my claim is that we will not
Burg, W. (Wibren) van der
core
SUMARIO: A.- El concepto. B.- Discusión del positivismo metódico del derecho. C.- Tareas. Bibliografía.
Müller, Friedrich +1 more
openaire +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
A design view of capability [PDF]
In order to optimise resource deployment in a rapid changing operational environment, capability has received increasing concerns in terms of maximising the utilisation of resources.
Boyle, Iain +4 more
core
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Islamic education encompasses not only worship but included in it is the aspect of using reason to understand God's creation and how the universe works. Science continues to develop and requires humans to be able to adapt to developments over time. Comte'
Yudha Okta Anuhgra
doaj +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Hartian Positivism and Normative Facts: How Facts Make Law II [PDF]
Mark Greenberg
openalex +1 more source

