Results 111 to 120 of about 160,506 (330)
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
This paper presents a reflection upon education according to the positivist philosophy particularly based on Comet's ideas. It starts out with an introduction about the emergence of the positivist philosophy and follows on with the topics "positivism ...
Jamil Ibrahim Iskandar, Maria Rute Leal
doaj
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Review of Post-Theory: Reconstructing Film Studies, edited by David Bordwell and Noël Carroll (Madison, Wisconsin: the University of Wisconsin Press, 1996) [PDF]
A review of Post-Theory: Reconstructing Film Studies, edited by David Bordwell and Noël Carroll (Madison, Wisconsin: the University of Wisconsin Press, 1996), xviii & 564 pages, $45.00 cloth, $17.95 paper, published on pages 492-494 of Philosophy ...
Cameron, Evan Wm.
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Siting Foreign Law: How Derrida Can Help [PDF]
Secondary spectrum access to TV white spaces is considered as a promising solution to relieve the spectrum shortage. In Europe, SE43 working group in CEPT is leading the discussion on the technical requirements for exploiting TV white spaces through the ...
Shi, Lei, Sung, Ki Won, Zander, Jens
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

