Results 71 to 80 of about 160,506 (330)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Law and economics, consequentialism and legal pragmatism: the influence of Oliver Holmes Jr. [PDF]
, 2012 This paper aims to present the similarities and differences between Posner's defense of Law and Economics (LAE) and Holmes' pragmatism. The investigation is centered in the arguments of economic consequences of judicial decisions.
Lima Catão, Adrualdo de
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PLURALISM OF LEGAL UNDERSTANDING IN RUSSIAN AND GLOBAL LEGAL DOCTRINE: BOUNDARIES OF LEGAL POSITIVISM AND THE NATURAL-LAW TRADITION [PDF]
, 2013 Sergey Nikolaevich Khrameshin
openalex +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Politikon, 2016 In the late 1980s, Robert Keohane argued that “the greatest weakness of the reflective school of international relations lies not in deficiencies in their critical arguments but in the lack of a clear reflective program that could be employed by ...
Cagla Luleci, I. Erkam Sula
doaj +1 more source
‘Plucking the Mask of Mystery from its Face’: Jurisprudence and H.L.A. Hart [PDF]
, 2007 Until recently, little was known of H.L.A. Hart\u27s private life. That has now changed with the publication of Nicola Lacey\u27s A Life of H.L.A. Hart: The Nightmare and the Noble Dream. Drawing on Hart\u27s notebooks and correspondence, Lacey paints an
Mikhail, John
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Normativity of law and interpretive approaches : (a discussion on the relation between law and reason) [PDF]
, 2012 The debates about the interrelations between reason and law have undergone a change after the eighteenth century. References to the recta ratio of jusnaturalistic tradition have not disappeared, but other comprehensions of legal reason have developed ...
Batalha, Carlos Eduardo
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SJOIANDER, Claire Turenne et Cox, Wayne S. (dir.). Beyond Positivism : Critical Reflections on International Theory. Boulder, Lynne Rienner, 1994, 213 p. [PDF]
, 1994 André C. Drainville
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source