Results 101 to 110 of about 500,195 (301)
The Best of All Possible Ends of the World: An Interview with Andrew Culp
(University of Minnesota Press, 2016) appears as an anomaly in English Deleuze scholarship. Andrew Culp contrasts Deleuze as a thinker of positivity who constantly demands we find “reasons to believe in this world” with a Deleuze of dark negativity.
Josef Thorne
doaj +1 more source
Aim: There are new publications stating that chronic infection may facilitate dysplastic changes and persistence of human papillomavirus (HPV)-DNA positivity.
Derya Sivri Aydın +3 more
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Positivity and equilibrium in a fractional SIR model with Mittag-Leffler memory
We present two slightly different constructions of a SIR model in which both the time taken to remove the individual from the infectious compartment and the infectivity have a memory according to Mittag-Leffler distributions.
N. Zeraick Monteiro +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Contributing factors of health-related preventive behaviors among resident aliens in China
BackgroundThe Belt and Road Initiative is promoting the growth of the cross-border population, and there is still a lack of study on modifiable factors associated with health-related preventive behaviors among resident aliens in China.
Jiayi LAI, Huishuan WU, Kezhi JIN
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Positivity: Identifiability and Estimability
Positivity, the assumption that every unique combination of confounding variables that occurs in a population has a non-zero probability of an action, can be further delineated as deterministic positivity and stochastic positivity.
Zivich, Paul N +2 more
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

