Results 111 to 120 of about 500,195 (301)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Clinical characteristics analysis of pertussis and Mycoplasma pneumoniae infection in children

Frontiers in Cellular and Infection Microbiology
ObjectiveTo analyze the clinical differences between pertussis and/or Mycoplasma pneumoniae (MP) infections in children and provide insights for clinical differential diagnosis.MethodsWe retrospectively reviewed children with respiratory symptoms who ...
Min Xue, Min Xue, Min Xue, Xiaoling Wei, Xiaoling Wei, Xiaoling Wei, Bing Wang, Bing Wang, Bing Wang, Miao Liu, Miao Liu, Miao Liu, Yun Zhang, Yun Zhang, Yun Zhang, Xiang Ma, Xiang Ma, Xiang Ma   +17 more
doaj   +1 more source

Positive Amalgamation

Logica Universalis, 2018
We study the amalgamation property in positive logic. We give some connections between the amalgamation property and Robinson theories, model-complete theories and the Hausdorff property.
openaire   +3 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The influence of positivity and self-efficacy beliefs on family functioning among young adults in Italy and Colombia

Frontiers in Psychology
BackgroundResearch suggests that positivity and self-efficacy beliefs may impact adaptive behavior and developmental outcomes, such as social adjustment and subjective wellbeing.
Roberto Baiocco, Jessica Pistella, Maryluz Gomez Plata, Mara Morelli, Stefano Isolani, Maryoris Elena Zapata Zabala, Kattia Paola Cabas Hoyos, Liliana Maria Uribe Tirado, Marcela Sucel Ruiz Garcia, Carmelina Paba Barbosa, Antonio Zuffiano, Maria Gerbino, Fiorenzo Laghi, Concetta Pastorelli   +13 more
doaj   +1 more source

Emotional priming of sentence comprehension: effects of a speaker’s static emotional expression and listener age [PDF]

, 2013
Carminati MN, Knoeferle P. Emotional priming of sentence comprehension: effects of a speaker’s static emotional expression and listener age. In: Knauff M, Pauen M, Sebanz N, Wachsmuth I, eds.
Pauen, Michael, Sebanz, Natalie, Wachsmuth, Ipke, Knoeferle, Pia, Knauff, Markus, Carminati, Maria Nella   +5 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Pathways to positivity from perceived stress in adolescents: multiple mediation of emotion regulation and coping strategies

, 2017
Background The current study aimed to examine the multiple mediation of emotion regulation and coping strategies in the relationship between perceived stress and positivity in adolescents.
Mehmet Ali Yildiz
core   +1 more source