Results 61 to 70 of about 500,195 (301)

A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates

open access: yesJournal of Causal Inference, 2019
A powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects.
Ghosh Debashis, Cruz Cortés Efrén
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Self-care and types of temporality of women during parental leave

open access: yesВестник Мининского университета
Introduction. During the period of parental leave, the mother's self-care is an indicator of her well-being, satisfaction with herself. Also undergoing changes are the temporal features of the mother, such as her time scenario, focus and attitude to time.
S. V. Dukhnovsky
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Positive definiteness and positive differences

open access: yesJournal of Combinatorial Theory, Series A, 1972
AbstractA previous inequality [2] in certain context, which holds in the application to the monotonicity of correlations in classical discrete Heisenberg ferromagnets with 2-dimensional spin [3], is extended to positive definiteness of a function on a group.
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Second-Order Nonstandard Finite Difference Method for a Malaria Propagation Model with Control

open access: yesAppliedMath
Standard numerical methods such as Runge–Kutta and Euler methods have been widely used to approximate solutions to nonlinear systems. These methods converge to the solution only for small step sizes; for larger time steps, they generally generate ...
Calisto B. Marime, Justin B. Munyakazi
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Investigating the relationship between positivity and meaning in the lives of cancer patients in Miandoab city

open access: yesروانشناسی ارتباطات
The aim of this study is to investigate the relationship between positivity and meaning in the lives of cancer patients in Miandoab city. The present research method is fundamental in terms of purpose and descriptive in terms of method of correlation ...
Samin Kalantari, Ali Shaker Dolog
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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