Results 71 to 80 of about 777,086 (291)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Inverse spectral positivity for surfaces

open access: yes, 2014
Let $(M,g)$ be a complete non-compact Riemannian surface. We consider operators of the form $\Delta + aK + W$, where $\Delta$ is the non-negative Laplacian, $K$ the Gaussian curvature, $W$ a locally integrable function, and $a$ a positive real number ...
Bérard, Pierre, Castillon, Philippe
core   +5 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Positive Properties of Green’s Function for Fractional Dirichlet Boundary Value Problem with a Perturbation Term and Its Applications

open access: yesFractal and Fractional
In this article, we study a fractional lower-order differential equation, −D0+αΥ(ξ)+a(ξ)Υ(ξ)=y(ξ),ξ∈(0,1),α∈(1,2), with a Dirichlet-type boundary condition, where a(ξ)∈L1[0,1] permits singularity.
Yongqing Wang
doaj   +1 more source

A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates

open access: yesJournal of Causal Inference, 2019
A powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects.
Ghosh Debashis, Cruz Cortés Efrén
doaj   +1 more source

Local Operator Multipliers and Positivity [PDF]

open access: yes, 2012
We establish an unbounded version of Stinespring's Theorem and a lifting result for Stinespring representations of completely positive modular maps defined on the space of all compact operators.
Steen, Naomi M.   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Positivity of hexagon perturbation theory

open access: yes, 2018
The hexagon-form-factor program was proposed as a way to compute three- and higher-point correlation functions in $\mathcal{N}=4$ super-symmetric Yang-Mills theory and in the dual AdS$_5\times$S$^5$ superstring theory, by exploiting the integrability of ...
de Leeuw, Marius   +5 more
core   +1 more source

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