Results 91 to 100 of about 383,296 (290)

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Comparison of 68Ga-DOTA-NaI3-Octreotide/tyr3-octreotate positron emission tomography/computed tomography and contrast-enhanced computed tomography in localization of tumors in multiple endocrine neoplasia 1 syndrome

World Journal of Nuclear Medicine, 2020
The optimum imaging modality for the screening of multiple endocrine neoplasia type 1 (MEN1)-associated tumors is not well established. Here, we compare the performance of contrast-enhanced CT (CECT) versus 68Ga DOTA-NOC/TATE PET/CT in MEN1 patients. The
Virendra Patil, Manjunath Goroshi, Hina Shah, Gaurav Malhotra, Priya Hira, Vijaya Sarathi, Vikram Lele, Swati Jadhav, Anurag Lila, Tushar Bandgar, Nalini Shah   +10 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Label‐Free SERS Fingerprinting of Neuroprotein Conformational Dynamics in Human Saliva

Advanced Materials, EarlyView.
Galvanic molecular entrapment (GME) is a label‐free method for detecting and quantifying neuroprotein conformational states. This technique enables direct surface binding and in situ hotspot generation around molecules, effectively overcoming challenges related to target localization and mismatched hotspot geometries.
Muhammad Shalahuddin Al Ja'farawy, Jun‐Yeong Yang, Chaewon Mun, Seunghun Lee, Chul Bum Cho, Yoo Hyun Um, Min‐Young Lee, Sung‐Gyu Park, Dong‐Ho Kim, Seung Ho Yang, Ho Sang Jung   +10 more
wiley   +1 more source

Time-course of effects of external beam radiation on [18F]FDG uptake in healthy tissue and bone marrow. [PDF]

, 2008
The utility of PET for monitoring responses to radiation therapy have been complicated by metabolically active processes in surrounding normal tissues.
Agazaryan, Nzhde, Czernin, Johannes, DeMarco, John J, Hsueh, Wei-Ann, Kesner, Adam L, Lau, Victoria K, Silverman, Daniel Hs, Speiser, Michael   +7 more
core  

Positively Charged Polymer‐Brush MOFs for Large‐Area, Pressure‐Resistant Gas Separation Membranes

Advanced Materials, EarlyView.
A universal POPA strategy enables positively charged polymer‐brush MOFs with self‐adaptive interfacial interlocking to resist aggregation under fast processing. This design ensures seamless dispersion within large‐area selective layers, achieving 1 m‐wide roll‐to‐roll fabrication of pressure‐resistant MMCMs with tunable CO2 separation performance ...
Yi Yang, Ye Yuan, Yuxiu Sun, Fei Shi, Chenyang Song, Weifan Wang, Qinghua Li, Menglong Sheng, Zhihua Qiao, Jingwei Hou, Anthony K. Cheetham, Zhi Wang   +11 more
wiley   +1 more source

Functional brain imaging : a brief overview of imaging techniques and their use in human and canine anxiety research [PDF]

, 2011
When used in combination with specific radioactive markers, functional imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) enable the visualization of several neurotransmitter receptors and
Audenaert, Kurt, De Meester, Rudy, Dobbeleir, André, Peremans, Kathelijne, van Bree, Henri, Vandermeulen, Eva, Vermeire, Simon   +6 more
core  

Plasmonic Nanomachines: Creating Local Potential Gradients and Motions

Advanced Materials, EarlyView.
Plasmonic nanomachines can generate optical, thermal, and chemical potential gradients to drive directional rectilinear, rotational, and twisting motions at the nanometer scale. The integration of multimodal plasmonic forces with functional materials and programmed structural distortions enables precise spatiotemporal actuation, thereby providing a ...
Yoonhee Kim, Soohyun Ji, Donghyun Choi, Jwa‐Min Nam   +3 more
wiley   +1 more source

Time resolution of the plastic scintillator strips with matrix photomultiplier readout for J-PET tomograph

, 2016
Recent tests of a single module of the Jagiellonian Positron Emission Tomography system (J-PET) consisting of 30 cm long plastic scintillator strips have proven its applicability for the detection of annihilation quanta (0.511 MeV) with a coincidence ...
3M Optical Systems, A Gajos, A Strzelecki, A Słomski, A Wieczorek, B Jasińska, D Alfs, D Kamińska, DeGroot M H, E Czerwiński, E Kubicz, Eljen Technology, Eriksson L, G Korcyl, General Electric, Hamamatsu, K Giergiel, L Raczyński, M Gorgol, M Pałka, M Silarski, M Zieliński, Mechler C L, Meijlink J R, Moskal P, Moskal P, Moskal P, Moszynski M, N G Sharma, N Zoń, Nickles R J, O Rundel, P Białas, P Kowalski, P Moskal, P Witkowski, Palka M, Philips, Saint Gobain Crystals, Schaart R D, Schaart R D, Seifert S, Spanoudaki V C, Surti S, Sz Niedźwiecki, Szymański K, T Bednarski, T Kozik, Townsend D W, W Krzemień, W Wiślicki, Z Rudy, Ł Kapłon   +52 more
core   +1 more source