Results 151 to 160 of about 216,080 (283)

Safety and effectiveness of the anti‐amyloid monoclonal antibody (mAb) drug lecanemab for early Alzheimer's disease: The pharmacovigilance perspective

British Journal of Clinical Pharmacology, EarlyView.
Abstract The development of humanized IgG1 anti‐amyloid monoclonal antibodies, such as lecanemab, provides a promising novel treatment pathway with potential disease‐modifying effects for patients with early Alzheimer's disease (AD). Lecanemab, which gained marketing approval by the United States Food and Drug Administration (US FDA) in July 2023, has ...
Amy Bobbins, Miranda Davies, Elizabeth Lynn, Debabrata Roy, Alison Yeomans, Saad A. W. Shakir   +5 more
wiley   +1 more source

MAINTENANCES OF POSITRON EMISSION TOMOGRAPHY AS A CLINICAL TOOL

, 1989
Yasuaki Shoji, Yasuo Aizawa, Takenori Hachiya, Eiichi Hagami, Hiroshi Onodera, Mikio Kan, Nobuo Sasaki, Hideto Toyoshima, Shigeki Sugawara   +8 more
openalex   +2 more sources

The Curious Concept That Almost Nobody Seemed to Care About at First: Virtual Particles in the Post‐War Period**

Berichte zur Wissenschaftsgeschichte, EarlyView.
Abstract Short‐lived, unobservable, and not subject to the usual rules of conservation of energy and momentum, virtual particles—an integral part of the conceptual framework of quantum field theory (QFT)—exhibit a number of curious characteristics which, in recent decades, have in part fueled important discussions about their ontological status ...
Jean‐Philippe Martinez
wiley   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

Radiosynthesis and evaluation of a 68Ga‐labeled brominated benzamide derivative for detection of melanoma in small animals

Bulletin of the Korean Chemical Society, EarlyView.
Malignant melanoma has the highest mortality rate among skin cancers due to its aggressiveness and metastatic potential, and early diagnosis is important because treatment options are limited. We synthesized a brominated benzamide derivative labeled with 68Ga and evaluated its biological properties as a PET imaging probe.
Dagyeong Hong, Chaewon Lee, Boreum Song, Eunsu Kim, Yejin Seo, Jiyu Kim, Wookyeong Jeong, Seong‐Young Kwon, Dong‐Yeon Kim, Ayoung Pyo   +9 more
wiley   +1 more source

The role of positron emission tomography in the evaluation and management of musculoskeletal lesions-a narrative review. [PDF]

Ann Jt
Puleo JM, Murtaza H, Thibodeau RM, Acosta EM, Cooley MR, DiCaprio MR.   +5 more
europepmc   +1 more source

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

BMEMat, EarlyView.
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen, Shijie Shangguan, Zhongyu Lin, Xuemei Zeng, Siew Yin Chan, Xian Qin, Shuangqian Yan   +6 more
wiley   +1 more source

Positron emission tomography in cardiac amyloidosis: current evidence and future directions. [PDF]

Heart Fail Rev
Aimo A, Ferrari Chen YF, Castiglione V, Passino C, Genovesi D, Giorgetti A, Emdin M, Vergaro G.   +7 more
europepmc   +1 more source

Mitochondria-Selective Reduction of 62Cu-Pyruvaldehyde Bis(N4-methylthiosemicarbazone)(62Cu-PTSM) in the Murine Brain; a Novel Radiopharmaceutical for Brain Positron Emission Tomography(PET) Imaging.

, 1993
Yasuhisa Fujibayashi, Kouichi Wada, Hiroshi Taniuchi, Yoshiharu Yonekura, J Konishi, Akira Yokoyama   +5 more
openalex   +2 more sources

A simple approach to biophysical profiling of blood cells in extranodal NK/T cell lymphoma patients using deep learning‐integrated image cytometry

BMEMat, EarlyView.
We developed a deep learning‐integrated image cytometry technique to profile biophysical attributes of blood cells from ENKTL patients. We demonstrate specific changes in cell size, eccentricity, and refractive index during treatment in a label‐free manner.
Seongcheol Park, Sang Eun Yoon, Youngho Song, Changyu Tian, Changi Baek, Hyunji Cho, Won Seog Kim, Seok Jin Kim, Soo‐Yeon Cho   +8 more
wiley   +1 more source