Results 111 to 120 of about 271,559 (315)

Combined evaluation of FDG-PET and MRI improves detection and differentiation of dementia. [PDF]

, 2011
INTRODUCTION: Various biomarkers have been reported in recent literature regarding imaging abnormalities in different types of dementia. These biomarkers have helped to significantly improve early detection and also differentiation of various dementia ...
Möller, Harald E, Dukart, J., Osama Sabri, Horstmann, A., Sabri, O., Harald E. Möller, Schroeter, Matthias L, Matthias L Schroeter, Barthel, H., Sabri, Osama, Juergen Dukart, Villringer, Arno, Dukart, Juergen, Müller, K. ; https://orcid.org/, Mueller, Karsten, Harald E Möller, Villringer, A. ; https://orcid.org/, Matthias L. Schroeter, Henryk Barthel, Karsten Mueller, Annette Horstmann, Arno Villringer, Barthel, Henryk, Schroeter, M. ; https://orcid.org/, Horstmann, Annette, Möller, H. ; https://orcid.org/   +25 more
core   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

Advanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza, Sheila Dakhel Plaza, Samuele Cazzamalli, Andrea Ciamarone, Andrea Galbiati, Riccardo Stucchi, Frederik Peissert, Emanuele Puca, Dario Neri, Ettore Gilardoni   +9 more
wiley   +1 more source

Correction to: The aluminium-[18F]fuoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules

EJNMMI Radiopharmacy and Chemistry, 2021
Stephen J. Archibald, Louis Allott
doaj   +1 more source

Randomized control trial of using tongue acupuncture in autism spectrum disorder

Journal of Traditional Chinese Medical Sciences, 2014
Objective: The therapeutic approach of traditional chinese Medicine (TCM) in autism spectrum disorder (ASD) is a functional one. To study the efficacy, safety and functional brain change from the use of tongue acupuncture (TAC) on ASD children.
Virginia Chun-Nei Wong, Jie-Guang Sun, David Wai-Chow Yeung   +2 more
doaj   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Positron Emission Tomography

, 2020
Positron emission tomography (PET) was clinically introduced in the 1970s and has since become one of the most important diagnostic imaging modalities in oncology.
Sekine, Tetsuro; https://orcid.org/, Hüllner, Martin W; https://orcid.org/, Mächler, P C, Pizzuto, Daniele A   +3 more
core   +1 more source

The application of positron emission tomography (PET/CT) in diagnosis of breast cancer. Part II. Diagnosis after treatment initiation, future perspectives [PDF]

, 2016
Similarly to the applications described in the first part of this publication, positron emission tomography with computed tomography (PET/CT) is also gaining importance in monitoring a tumour’s response to therapy and diagnosing breast cancer recurrences.
Grażyna Jarząbek, Elżbieta Jodłowska, Agata Czarnywojtek, Amanda Rewers, Witold Kędzia, Rafał Czepczyński, Marek Ruchała   +6 more
core   +1 more source

Orthogonal Ionic Liquid‐Based Extraction Strategy Enables Amyloid‐Specific Profiling of Aggregate Proteome

Advanced Science, EarlyView.
An orthogonal ionic‐liquid extraction (Orth‐iEA) enables selective isolation of amyloid fibrils. TMGBF4 disrupts hydrogen‐bonded β‐sheet networks to solubilize amyloid aggregates, whereas C12ImCl interacts with hydrophobic regions of non‐amyloid proteins.
Shiying Zheng, Ye Liu, Bowen Zhong, Huiying Chu, Zhou Gong, Baofeng Zhao, Mengchun Cheng, Zhen Liang, Yukui Zhang, Qun Zhao, Lihua Zhang   +10 more
wiley   +1 more source

Cardiac positron emission tomography (PET)

, 2011
Introduction to cardiac positron emission tomography (PET) 212PET instrumentation (1) 214PET instrumentation (2) 216Radiopharmaceuticals for cardiac PET (1) 218Radiopharmaceuticals for cardiac PET (2) 220Interpretation and clinical significance of ...
Nikant Sabharwal, Chee Yee Loong, Andrew Kelion   +2 more
core   +1 more source