Results 151 to 160 of about 1,853,110 (305)

[Positron emission tomography in pharmacokinetics and pharmacodynamics]

open access: yes, 1993
Positron emission tomography (PET) allows the non invasive and quantitative measurement of regional distribution of molecules labeled with positron emitting isotopes such as: nitrogen, oxygen, carbon and fluorine.
G. Lucignani, F. Fazio, R. M. Moresco
core   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm   +2 more
wiley   +1 more source

Whole Body Positron Emission Tomography with 18f-Fluoro-2-Deoxyglucose for the Detection of Recurrent Ovarian Cancer

open access: yes, 2009
Although many cancers can be detected by whole-body positron emission tomography (PET) with 18F-fluoro-2-deoxyglucose ( FDG), there has been limited clinical experience with FDG- PET for the detection of recurrent ovarian cancers.
顏若芳, YEN, RUOH-FANG
core  

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia   +16 more
wiley   +1 more source

Segmenting Extra Pulmonary Tuberculous Lesions in Computed Tomography Images Using Positron Emission Tomography Intensity Markers

open access: yes, 2009
Segmenting Extra Pulmonary Tuberculous Lesions in Computed Tomography Images Using Positron Emission Tomography Intensity ...
MI Saripan (15878771)   +5 more
core  

Image reconstruction by inhomogeneous diffusion for positron emission tomography

open access: yes, 2006
In positron emission tomography (PET), image reconstruction is a demanding problem. Since, PET image reconstruction is an ill-posed inverse problem, new methodologies need to be developed.
Mondal, Partha Pratim, Rajan, K
core  

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg   +7 more
wiley   +1 more source

Image Enhancement In Positron Emission Tomography Using Expectation Maximization

open access: yes, 2006
Positron Emission Tomography (PET) tomography is one of the imaging modality. PET Tomography scanners collect measurements of a patient's in vivo radiotracer distribution. These measurements are reconstructed into cross-sectional images.
Erol, H., Koklukaya, E., Alkan, A.
core  

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

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