Results 191 to 200 of about 557,117 (392)

Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths

Annals of Neurology, EarlyView.
Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian, Corrina S. Fonseca, Adam C. Martersteck, Yishu Chao, Yuheng Chen, Daniela Ushizima, Duygu Tosun, Lea T. Grinberg, Kevin S. Weiner, William J. Jagust, for the Alzheimer's Disease Neuroimaging Initiative   +10 more
wiley   +1 more source

Individualized Atrophy‐Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed‐Effects Modeling

Annals of Neurology, EarlyView.
Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt, Dana Leichter, Yann Cobigo, Amy Wolf, John Kornak, Annie Clark, Lucy L. Russell, Arabella Bouzigues, David M. Cash, Martina Bocchetta, Molly Olzinski, Brian Appleby, Ece Bayram, Barbara Borroni, Andrea Bozoki, Chris R. Butler, David Clark, Rhian S. Convery, R. Ryan Darby, Alexandre de Mendonça, Bradford Dickerson, Kimiko Domoto‐Reilly, Simon Ducharme, Eve Ferry‐Bolder, Elizabeth Finger, Phoebe H. Foster, Douglas R. Galasko, Daniela Galimberti, Alexander Gerhard, Nupur Ghoshal, Caroline Graff, Neill Graff‐Radford, Ian M. Grant, Chadwick M. Hales, Lawrence S. Honig, Ging‐Yuek Hsiung, Edward D. Huey, David Irwin, Lize C. Jiskoot, Walter Kremers, Justin Y. Kwan, Robert Laforce, Isabelle Le Ber, Gabriel C. Léger, Johannes Levin, Irene Litvan, Ian R. Mackenzie, Mario Masellis, Mario F. Mendez, Fermin Moreno, Chiadi Onyike, Markus Otto, Belen Pascual, Peter Pressman, Rosa Rademakers, Eliana Marisa Ramos, Aaron Ritter, Erik D. Roberson, James B. Rowe, Raquel Sanchez‐Valle, Isabel Santana, Harro Seelaar, Allison Snyder, Sandro Sorbi, Matthis Synofzik, Maria Carmela Tartaglia, Pietro Tiraboschi, John C. van Swieten, Marijne Vandebergh, Rik Vandenberghe, Hilary W. Heuer, Bruce L. Miller, William W. Seeley, Maria Luisa Gorno‐Tempini, Joel H. Kramer, Leah Forsberg, Kejal Kantarci, Bradley F. Boeve, Adam L. Boxer, Jonathan D. Rohrer, Howard J. Rosen, Adam M. Staffaroni, FTD Prevention Initiative (FPI) investigators   +82 more
wiley   +1 more source

Dual Modality Semiconducting Polymer Nanoparticles for Use in Optical and Magnetic Resonance Imaging

Advanced NanoBiomed Research, EarlyView.
Well‐defined dual‐modality semiconducting polymer nanoparticles composed of red‐emitting conjugated polymers functionalized with novel gadolinium‐based contrast agents have been prepared. The assemblies show a greatly enhanced relaxivity performance compared to the clinical standard, Dotarem, while offering ultrabright fluorescence, ideal for optical ...
Faysal A. Farah, Yu Qin, Xin Shi, Dylan M. Owen, Mark A. Green, James D. E. T. Wilton‐Ely   +5 more
wiley   +1 more source

Complementary Value of Cardiac Magnetic Resonance Imaging and Positron Emission Tomography/Computed Tomography in the Assessment of Cardiac Sarcoidosis

Circulation Cardiovascular Imaging, 2018
Tomas S Vita, D. Okada, Mahdi Veillet-Chowdhury, P. Bravo, Erin Mullins, E. Hulten, M. Agrawal, R. Madan, V. Taqueti, M. Steigner, H. Skali, R. Kwong, G. Stewart, S. Dorbala, M. D. Di Carli, R. Blankstein   +15 more
semanticscholar   +1 more source

Economic Evaluation of Positron Emission Tomography (PET) in Non Small Cell Lung Cancer (NSCLC), CHERE Working Paper 2007/6 [PDF]

Background: There are several perceived benefits from introducing positron emission tomography (PET) scanning into the staging of non small lung cancer (NSCLC).
Alex Bird, Richard Norman, Stephen Goodall   +2 more
core  

Characterizing amyloid and tau positron emission tomography-based stages across the clinical continuum. [PDF]

Alzheimers Dement
Cody KA, Sokołowski A, Johns E, Guerra LM, Winer JR, Young CB, Younes K, Dumitrescu L, Archer DB, Durant A, Sathe A, Koran MEI, Mez J, Saykin AJ, Toga A, Cuccaro M, Tosun D, Insel PS, Johnson SC, Harrison TM, Hohman TJ, Mormino EC.   +21 more
europepmc   +1 more source

Genetic and Sex Associations with Earlier Estimated Onset of Amyloid Positivity from over 4000 Harmonized Positron Emission Tomography Images [PDF]

Tonnar Castellano, Tianyu Wang, Emma Nolan, Derek B. Archer, Karly Alex Cody, Theresa M. Harrison, Yiyang Wu, Alaina Durant, Vaibhav A. Janve, Corinne D. Engelman, William Jagust, Marilyn Albert, Sterling C. Johnson, Susan M. Resnick, Reisa A. Sperling, Murat Bilgel, Andrew J. Saykin, Badri N. Vardarajan, Richard Mayeux, Tobey J. Betthauser, Logan Dumitrescu, Elizabeth C. Mormino, Timothy J. Hohman, Mary Ellen I. Koran   +23 more
openalex   +1 more source

Genome‐Wide DNA Methylation Study Reveals Specific Signatures in the Affected Arterial Tissue of Patients With Giant Cell Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis. Methods DNA methylation profiling was analyzed in 79
Gonzalo Borrego‐Yaniz, Ana Márquez, Elkyn Estupiñán‐Moreno, Laura C. Terrón‐Camero, Miguel A. González‐Gay, Santos Castañeda, Giuliana Guggino, David Saadoun, Pietro Lio, Simona Fontana, Martina Bonacini, Alessandro Rossi, Alberto Cavazza, Francesco Muratore, Carlo Salvarani, Nicolo Pipitone, Javier Martin, Stefania Croci, Lourdes Ortiz‐Fernández   +18 more
wiley   +1 more source

Brain glial activation in fibromyalgia – A multi-site positron emission tomography investigation

Brain, behavior, and immunity, 2019
D. Albrecht, A. Forsberg, Angelica Sandström, C. Bergan, D. Kadetoff, E. Protsenko, J. Lampa, Yvonne C. Lee, C. O. Höglund, C. Catana, S. Cervenka, O. Akeju, M. Lekander, George Cohen, C. Halldin, N. Taylor, Minhae Kim, J. Hooker, R. Edwards, V. Napadow, E. Kosek, M. Loggia   +21 more
semanticscholar   +1 more source

Lhermitte-Duclos disease presenting with positron emission tomography-magnetic resonance fusion imaging: a case report [PDF]

, 2012
Ferdinando Calabria, Giovanni Grillea, Maddalena Zinzi, Manlio Barbarisi, Emanuele Siravo, Marcello Bartolo, Giampaolo Cantore, Claudio Colonnese, Cristina Grasso, Orazio Schillaci   +9 more
openalex   +1 more source