Results 201 to 210 of about 1,853,110 (305)

Salvage Metastasis-Directed Therapy Without Androgen Deprivation for Positron Emission Tomography-Defined Oligorecurrent Prostate Cancer: Results of the SOAR Phase II Trial. [PDF]

open access: yesJU Open Plus
Crockett E   +22 more
europepmc   +1 more source

Frequent cannabis use and the association with seizure burden in drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Cannabis use has increased substantially, with modern products characterized by high tetrahydrocannabinol concentrations and variable composition. The relationship between frequent cannabis use and epilepsy outcomes remains uncertain. We examined the association between frequent cannabis use and epilepsy severity, clinical phenotype,
Santiago Philibert‐Rosas   +16 more
wiley   +1 more source

How should etiology change the classification of the epilepsies? Report from the ILAE 2021–2025 Terminology Commission

open access: yesEpilepsia, EarlyView.
Abstract The classification of the epilepsies has traditionally relied on clinical and electroencephalographic features. However, advancements in molecular genetics, neuroimaging, and our understanding of epilepsy pathophysiology necessitate a shift toward an etiology‐based approach.
Nicola Specchio   +15 more
wiley   +1 more source

Redefining Soft Tissue Sarcoma Imaging: The Expanding Role of Positron Emission Tomography/Computed Tomography: A Review. [PDF]

open access: yesWorld J Nucl Med
Tamimi ASA   +8 more
europepmc   +1 more source

Multimodal modeling of the ictal onset zone in refractory insular epilepsy and seizure outcome of magnetic resonance‐guided laser interstitial therapy: A pediatric single‐center retrospective study

open access: yesEpilepsia, EarlyView.
AbstractObjectiveThis study was undertaken to evaluate seizure outcomes after magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) in children with insular epilepsy and to assess how the extent of ablation overlaps with multimodal definitions of the ictal onset zone (IOZ).MethodsWe conducted a retrospective, single‐center study ...
Lelio Guida   +15 more
wiley   +1 more source

Selective γ8 transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein negative allosteric modulators: Efficacy in preclinical antiseizure models

open access: yesEpilepsia, EarlyView.
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta   +5 more
wiley   +1 more source

Temporal Trends of Metastatic Prostate Cancer in the Prostate-Specific Membrane Antigen Positron Emission Tomography Era in the United States. [PDF]

open access: yesProstate
Quarta L   +15 more
europepmc   +1 more source

Reasons for not reoperating and outcomes of reoperation after seizure recurrence in pediatric epilepsy surgery: A population‐based study

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy surgery is an established and effective treatment for children with drug‐resistant epilepsy. Although the majority of patients become seizure‐free postoperatively, 20%–40% experience seizure recurrence. Although repeat surgery can achieve seizure freedom in selected cases, the reasons children with seizure recurrence do not ...
Vincent Zheng   +5 more
wiley   +1 more source

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