Results 21 to 30 of about 604,820 (405)

Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1898-1909, December 2022., 2022
Abstract Objectives Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by a fully automated immunoassay platform, and brain β‐amyloid (Aβ ...
Hisashi Nojima   +9 more
wiley   +1 more source

The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules

open access: yesEJNMMI Radiopharmacy and Chemistry, 2021
The aluminium-[18F]fluoride ([18F]AlF) radiolabelling method combines the favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal-based radiochemistry and has been used to parallel gallium-68 radiopharmaceutical ...
Stephen J. Archibald, Louis Allott
doaj   +1 more source

Many-body theory of positron binding in polyatomic molecules [PDF]

open access: yesNature, 606, 688 (2022), 2021
Positrons bind to molecules leading to vibrational excitation and spectacularly enhanced annihilation. Whilst positron binding energies have been measured via resonant annihilation spectra for $\sim$90 molecules in the past two decades, an accurate \emph{ab initio} theoretical description has remained elusive.
arxiv   +1 more source

COVID‐19‐related encephalopathy: a case series with brain FDG‐positron‐emission tomography/computed tomography findings

open access: yesEuropean Journal of Neurology, 2020
The aim of this paper is to describe the clinical features of COVID‐19‐related encephalopathy and their metabolic correlates using brain 2‐desoxy‐2‐fluoro‐D‐glucose (FDG)‐positron‐emission tomography (PET)/computed tomography (CT) imaging.
C. Delorme   +16 more
semanticscholar   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh   +5 more
wiley   +1 more source

The anterior nucleus of the thalamus plays a role in the epileptic network

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2010-2024, December 2022., 2022
Abstract Objectives We investigated both the metabolic differences and interictal/ictal discharges of the anterior nucleus of the thalamus (ANT) in patients with epilepsy to clarify the relationship between the ANT and the epileptic network. Methods Nineteen patients with drug‐resistant epilepsy who underwent stereoelectroencephalography were studied ...
Hao Yan   +9 more
wiley   +1 more source

A heterogeneous phantom study for investigating the stability of PET images radiomic features with varying reconstruction settings

open access: yesFrontiers in Nuclear Medicine, 2023
The purpose of this work was to assess the capability of radiomic features in distinguishing PET image regions with different uptake patterns. Furthermore, we assessed the stability of PET radiomic features with varying image reconstruction settings.
Emad Alsyed   +5 more
doaj   +1 more source

The role of artificial intelligence based on PET/CT radiomics in NSCLC: Disease management, opportunities, and challenges

open access: yesFrontiers in Oncology, 2023
ObjectivesLung cancer has been widely characterized through radiomics and artificial intelligence (AI). This review aims to summarize the published studies of AI based on positron emission tomography/computed tomography (PET/CT) radiomics in non-small ...
Qiuyuan Hu   +8 more
doaj   +1 more source

Review of nuclear medicine methods applied in diabetology. [PDF]

open access: yes, 2020
The aim of this paper is to present the most relevant clinical applications of positron emission tomography/computed tomography, scintigraphy and single photon emission tomography with different radiotracers allowing to visualize e.g. glucose metabolism,
Bocer, Natalia   +7 more
core   +2 more sources

Habitat Imaging-Based 18F-FDG PET/CT Radiomics for the Preoperative Discrimination of Non-small Cell Lung Cancer and Benign Inflammatory Diseases

open access: yesFrontiers in Oncology, 2021
PurposeTo propose and evaluate habitat imaging-based 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) radiomics for preoperatively discriminating non-small cell lung cancer (NSCLC) and benign inflammatory ...
Ling Chen   +5 more
doaj   +1 more source

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