Results 61 to 70 of about 1,912,136 (307)

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Central hyperthyroidism due to an ectopic TSH-secreting pituitary tumor: a case report and literature review

Frontiers in Endocrinology
Ectopic thyroid-stimulating hormone (TSH)-secreting tumors are extremely rare, with only 15 reported cases in the literature. Herein, we described a 60-year-old female patient with thyrotoxicosis and elevated or unsuppressed levels of TSH. Family history
Chonggui Zhu, Tong Liu, Haonan Yu, Lina Chang, Xiaona Zhang, Jia Yao, Geng Zhang, Qiusong Chen, Qing He, Ming Liu   +9 more
doaj   +1 more source

Models for the PET quantitative imaging of the adenosine receptor radioligand [11C] SCH442416 in humans [PDF]

, 2010
Positron Emission Tomography is an important imaging technique, that enables regional function to be assayed in a fully quantitative and noninvasive manner. It is based on the use of radioactive tracers: [11C]SCH442416, which is the compound of interest
Boscolo Galazzo, Ilaria
core  

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey [PDF]

, 2014
We investigated the use of Alzheimer's disease (AD) biomarkers in European Alzheimer's Disease Consortium centers and assessed their perceived usefulness for the etiologic diagnosis of mild cognitive impairment (MCI).
Erikdotter, M, Samantha Galluzzi, Peters, Oliver, Galluzi, S, Andreas Monsch, Jones, Roy W, Mehrabian, S., Zekry, Dina, Wilcock, G, Sarazin, M., Sánchez-Castellano, Carmen, Martinez-Lage, P, Kehoe, P.G., Wallin, Åsa,, Hallikainen, M., Monsch, A, Santana, I, Felician, O, Frolich, L, Rikkert, M.O., Isabel Santana, Wilcock, Gordon, Jean‐Marc Orgogozo, Flavio Nobili, Mecocci, P, Hausner, Lucrezia, Roy W. Jones, Jessen, F., Heuser, I., Isabell Heuser, Eric Salmon, David Wilkinson, Froelich, L., Félician, Olivier, Maria Eriksdotter, Ceccaldi, M, Sarazin, M, Olde Rikkert, Marcel, de Mendonca, A., Aguera, E., Galluzzi, Samantha, Felician, O., Pasquier, F., Patrick Gavin Kehoe, Wolf, H, Nordberg, Agneta, Shima Mehrabian, Latchezar Traykov, Frolich, L., Mira Didic, Dartigues, Jean François, Hasselbalch, S.G., Aguera, Eduardo, Alberto Lleo, Sarazin, Marie, Martina Bocchetta, Brian Lawlor, Wallin, Åsa K, Dartigues, J.F., Monsch, A., Magda Tsolaki, Wilkinson, D., Giovanni B. Frisoni, Sanchez-Castellano, C, Yener, Goersev, NOBILI, FLAVIO MARIANO, Nobili, Flavio, Eriksdotter, Maria, Bernabei, R, Hallikainen, M, Gertz, H.J., Frisoni, Giovanni B., Lleo, A, Eduardo Aguera, Hallikainen, Merja, Roberto Bernabei, Alexandre de Mendonça, Gordon Wilcock, Visser, Pieter Jelle, Bullock, R., Frisoni, G.B., Bernabei, Roberto, Jones, Roy W., Alexander Kurz, Sanchez-Castellano, C., Wallin, Åsa, Bochetta, M, Bullock, R, Martinez-Lage, P., Patrizia Mecocci, Frank Jessen, Lleo, Alberto, Ceccaldi, M., Pablo Martinez‐Lage, Nobili, F., Florence Pasquier, Salmon, E., Eriksdotter, M., Lawlor, B., de Mendonça, Alexandre, Dartigues, Jean-François, Jessen, F, Pasquier, Florence, Marie Sarazin, Lucrezia Hausner, Monsch, Andreas, Rikkert, Marcel Olde, Dina Zekry, Carmen Sánchez‐Castellano, Pasquier, F, Traykov, L., Didic, M., Tsolaki, M, Nordberg, A., Pieter Jelle Visser, Kehoe, Patrick Gavin, Orgogozo, J.M., Froelich, Lutz, Kurz, A, Nobili, F, Bocchetta, M., Lund University., Martinez-Lage, Pablo, Agneta Nordberg, Åsa K. Wallin, Hasselbalch, Steen G, Zekry, D., Wilkinson, D, Gertz, Hermann Josef, Ceccaldi, Mathieu, Galluzzi, S., Santana, Isabel, Wilcock, G., Lleo, A., Mehrabian, S, Kurz, A., Heuser, Isabell, Gertz, Hermann-Josef, Kurz, Alexander, Wilkinson, David, Jean‐François Dartigues, Oliver Peters, Hausner, L, Mecocci, Patrizia, Peters, O., Roger Bullock, Lutz Frölich, Frisoni, Giovanni B, Merja Hallikainen, Orgogozo, Jean Marc, Jones, R.W., Henrike Wolf, Nordberg, A, Mecocci, P., Olde Rikkert, M, Olivier Félician, Wolf, Henrike, Bullock, Roger, Yener, G, Wallin, Åsa K., Peters, O, Yener, Görsev, Wolf, H., Didic, Mira, Mathieu Ceccaldi, Hausner, L., de Mendonca, A, Lawlor, Brian, Jessen, Frank, Orgogozo, Jean-Marc, Bernabei, R., Marcel Olde Rikkert, Mendonca, A. de, Heuser, I, Mehrabian, Shima, Salmon, Eric, Traykov, L, Visser, P.J., Bocchetta, Martina, Aguera, E, Martinez Lage, Pablo, Frölich, Lutz, Hermann‐Josef Gertz, Steen G. Hasselbalch, Didic, M, Tsolaki, M., Tsolaki, Magda, Hasselbalch, Steen G., Santana, I., Hasselbach, S.G., Lawlor, B, Olde Rikkert, M.G.M., Yener, G., Görsev Yener, Wallin, A.K., Traykov, Latchezar, Sänchez Castellano, Carmen, Ceccaldi M, Monsch A, Frisoni GB, Santana I, Lawlor B, Bernabei R, Nordberg A, Lleo A, Zekry D, Kurz A, Rikkert MO, Visser PJ, Galluzzi, S, Kehoe PG, Jones RW, Salmon E, Kehoe, PG, Peters O, Wilkinson D, Jessen F, Hausner L, Martinez Lage P, Olde Rikkert M, Martinez-Lage P, Heuser I, Mehrabian S, Aguera E, Mecocci P, Wolf H, EADC survey, Tsolaki M, Bocchetta, M, Bocchetta M, Dartigues JF, de, Mendonca A, Traykov L, Félician O, Sánchez-Castellano C, Hallikainen M, Sánchez Castellano C, Galluzzi S, Gertz HJ, Pasquier F, Hasselbalch SG, Bullock R, Didic M, Wallin AK, Frölich L, de Mendonça A, Wilcock G, Dartigues, J-F, Nobili F, Orgogozo JM, Yener G, Sarazin M, Eriksdotter M   +252 more
core   +1 more source

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham, Casey Vanderlip, Colin Birkenbihl, Eashwar Krishna, Chizobam Ugboaja, Andrew E. Budson, Brandon Frank, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter, Hans Dorn, Julian Hellmann‐Regen, Ana Bueno‐Lopez, Verena van Ginneken, Heidi Danker‐Hopfe   +5 more
wiley   +1 more source

The Role of 18F-FDG-PET and PET/CT in Patients with Colorectal Liver Metastases Undergoing Selective Internal Radiation Therapy with Yttrium-90: A First Evidence-Based Review

The Scientific World Journal, 2014
Purpose. To provide a first evidence-based review of the literature on the role of fluorine-18-fluorodeoxyglucose positron emission tomography and positron emission tomography/computed tomography (FDG-PET and PET/CT) in patients with colorectal liver ...
Salvatore Annunziata, Giorgio Treglia, Carmelo Caldarella, Federica Galiandro   +3 more
doaj   +1 more source

PET/CT in paediatric malignancies - An update

Indian Journal of Medical and Paediatric Oncology, 2016
18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is a well-established imaging modality in adult oncological practice. Its role in childhood malignancies needs to be discussed as paediatric malignancies differ from adults in tumor subtypes ...
Subramanyam Padma, Palaniswamy Shanmuga Sundaram, Anshu Tewari   +2 more
doaj   +1 more source

Positron-Emission Tomography [PDF]

, 1997
We review positron-emission tomography (PET), which has inherent advantages that avoid the shortcomings of other nuclear medicine imaging methods. PET image reconstruction methods with origins in signal and image processing are discussed, including the ...
Fessler, Jeffrey A., Ollinger, John M.
core   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source