Results 111 to 120 of about 1,079,106 (302)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Scrambled and distributionally scrambled n-tuples [PDF]
, 2013 This article investigates the relation between the distributional chaos and the existence of a scrambled triple. We show that for a continuous mapping $f$ acting on a compact metric space $(X,d)$, the possession of an infinite extremal distributionally ...
Doleželová, Jana
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Studies in African Languages and Cultures, 2000 During my work on sentence schemata in Amharic the problem of formal description of the construction expressing "possession" appeared. Sentence schemata based on verbal centre required the verb ‘ to have’.
Laura Łykowska
doaj
Efficient allocation of property rights on the planet Mars [PDF]
, 2008 This paper examines the need to foster competition in the exploration of the solar system through the motivation of private profit, in contrast to the concepts of communal ownership of space resources as expressed in international treaty law.
Collins, D. A.
core
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Antípoda: Revista de Antropología y Arqueología, 2012 The topics developed in this essay are: Mythological memory and the subsistence of traditional cultures; colonialism and the destruction of mythological memories; Christian conversion, and the collapse of the American cosmos. The opposition of mythos and
Eduardo Subirats
doaj
Regulation and Deregulation: Property Rights Allocation Issues in De Regulation of Common Pool Resources [PDF]
Rights-based institutions have been adopted for certain natural resources in order to more effectively mitigate the losses of the common pool. Past central government (command and control) regulation has not proved satisfactory.
Gary Libecap
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source