Results 41 to 50 of about 4,976 (285)

Predicative Possessive Constructions in Hindi

open access: yesBhasha, 2022
Hindi has more than one construction for the encoding of possessive relationships: in particular, this language lacks a nominative‑accusative construction and a ‘have’‑verb, and instead encodes possession through intransitive sentences with the ...
Carnesale, Lucrezia
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

KONSTRUKSI POSESIF BAHASA INDONESIA DALAM RUBRIK SURAT PEMBACA

open access: yesLitera, 2016
This study aims to describe characteristics of the relationship between the possessor and the possessed in Indonesian possessive constructions in letters to the editor.
Teguh Setiawan
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

MIXED METHOD: STUDENTS’ ABILITY IN APPLYING POSSESSIVE PRONOUN IN WRITING SENTENCES AT THE 1ST SEMESTER FKIP UNILAK PEKANBARU

open access: yesLectura: Jurnal Pendidikan, 2017
As the students of English Department, the students should be able in doing grammarwell, in this case Possessive Pronoun. The purpose of this research was to find out the students’ability in applying Possessive Pronoun and their common problem in ...
Syahdan Syahdan
doaj  

La expansión del posesivo pospuesto a la luz de documentación navarra (y aragonesa) del siglo XIII

open access: yesScripta: Revista Internacional de Literatura i Cultura Medieval i Moderna, 2016
En los primitivos documentos romances el posesivo sólo aparece antepuesto al sustantivo (“(el) nuestro padre”). La posposición (“padre nuestro”) se empieza a registrar en el siglo XIII en aragonés y en dialecto navarro.
Ángeles Romero Cambrón
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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