Results 41 to 50 of about 79,780 (296)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Whose name is it anyway? Varying patterns of possessive usage in eponymous neurodegenerative diseases [PDF]

PeerJ, 2013
There has been long-standing debate over whether use of the possessive form of the names of eponymous neurological disorders should be abandoned. Which view has actually predominated in practice?
Michael R. MacAskill, Tim J. Anderson
doaj   +2 more sources

Wittgenstein on Sameness, Necessity and Privacy [PDF]

, 2002
The aim of this paper is to examine Wittgenstein"s arguments against the meaningfulness of statements which state the possessive privacy of sensations; and to demonstrate their ...
Rami, Adolf
core  

Anti-Nirvana: crime, culture and instrumentalism in the age of insecurity [PDF]

, 2005
‘Anti-Nirvana’ explores the relationship between consumer culture, media and criminal motivations. It has appeared consistently on the list of the top-ten most-read articles in this award-winning international journal, and it mounts a serious neo ...
Baudrillard, J., Bauman, Z., Bauman, Z., Beck, U., Beck, U., Bourdieu, P., Bourdieu, P., Byrne, D., Castells, M., Chesney-Lind, M., Davis, M., Debord, G., Downes, D., Eagleton, T., Elias, N., Faludi, S., Fletcher, J., Freud, S., Freud, S., Gray, J., Habermas, J., Hall, S., Hall, Steve, Hobsbawm, E., Horne, R., Hutton, W., Jenks, C., Lasch, C., Lasch, C., Lea, J., MacInnes, J., Miller, W. B., Shover, N., Simon Winlow, Steve Hall, Sumner, C., Taylor, I., Westergaard, J. H., Willis, P., Wilson, W. J., Winlow, S., Winlow, S., Winlow, S., Young, J.   +43 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Social Criticism and the Exclusion of Ethics [PDF]

, 2008
As Axel Honneth has recently noted, the critical concerns of social philosophers during the past three decades have been focused primarily on questions of justice, with ethical issues about the human good being largely excluded.
Keat, Russell
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Animacy and Alienability: A Reconsideration of English Possession [PDF]

, 2016
Current scholarship on English possessive constructions, the s-genitive and the of-construction, largely ignores the possessive relationships inherent in certain English compound nouns. Scholars agree that, in general, an animate possessor predicts the s-
Jones, Jaimee
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Expressing possession with HAVE and BE: affected possession structures in Flemish [PDF]

, 2015
This paper concerns a cartographic account of Flemish Event Possessives (FEVPs) which alternate between a variety with HAVE and one with BE. The FEVP matrix subjects have the interpretation of both being the Possessor (in its broadest meaning) of the ...
Buelens, Liisa
core   +1 more source