Results 71 to 80 of about 1,678 (303)

An analysis on the students’ possessives mastery at grade VII SMP NEGERI 4 Padang Bolak [PDF]

open access: yes, 2014
This study is talking about the students’ mastery in possessives at grade VII SMP Negei 4 Padangbolak. The purpose of this research is to describe the students’ possessives mastery at grade VII SMP Negeri 4 Padangbolak, to identify the students ...
Morbeini, Fitri
core  

Comprehensive supersense disambiguation of English prepositions and possessives [PDF]

open access: yes, 2018
Semantic relations are often signaled with prepositional or possessive marking—but extreme polysemy bedevils their analysis and automatic interpretation.
Blodgett, Austin   +8 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Property, possession and knowledge [PDF]

open access: yesSSRN Electronic Journal, 2016
As Hodgson has nicely pointed out, capitalism can be only understood if we accept that, unlike possession, property is a social construction and a relation among individuals. Unlike possession, property does not require a material thing on which it should be applied. Property rights can create fictitious commodities on intangible assets symbolizing the
openaire   +3 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

3rd person possessives: Old Portuguese and Modern Brazilian Portuguese

open access: yesFilologia e Linguística Portuguesa, 2014
This paper addresses some comparative aspects of the 3rd person possessive pronouns seu and dele in Modern Brazilian Portuguese (BP) and Old Portuguese (OP).
Maria Aparecida Torres Morais   +1 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The acquisition of Hungarian recursive possessives [PDF]

open access: yes
The objective of this paper is to address two principal inquiries. The first question to be addressed is the age at which children begin to comprehend and produce recursive possessives in a manner that is consistent with the adult data.
Langó-Tóth, Ágnes
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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