Results 201 to 210 of about 3,919,087 (316)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Upper brachial plexus lesions in adults: long term results of direct infraspinatus muscle reinnervation with a radial nerve branch transfer. [PDF]

Brain Spine
Siqueira MG, Martins RS, de Oliveira KF, de Freitas BSAG, Heise CO.   +4 more
europepmc   +1 more source

Necessity and Possibility in Management Sciences

Physics relies on nomological laws (e.g., Newton’s laws), considered necessary within a given framework. Management sciences, in contrast, operate in a world shaped by human behavior, institutions, and environments.
Necessity and Possibility in Science, 5th workshop of the OLOFOS group, Manwana Sindani, Dieu-Merci   +1 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Inclusion Possibilities

TechTrends, 2023
openaire   +2 more sources

Lateral cutaneous nerve entrapment syndrome associated with appendicitis. [PDF]

J Surg Case Rep
Kawahara K, Kataoka Y, Miyagawa T, Watari T.   +3 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Beyond integration: towards benchmarks for developmental potential in human stem cell-derived embryo models. [PDF]

Hum Reprod Update
Luijkx DG, Ashtar L, de Graeff N, Coonen E, Giselbrecht S, de Wert GMWR, Vrij EJ, Grant R, Pereira Daoud AM.   +8 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Dupilumab-Associated Severe Headaches in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP): A Report of Two Cases With Resolution After Cessation. [PDF]

Cureus
Wang M, Marcus S.
europepmc   +1 more source