Results 91 to 100 of about 1,723,317 (301)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
World is Open for Everybody: Is It Possible to Turn Accessible Tourism into a Business in Russia? (Case Study) [PDF]
, 2016 Yulia Aray +1 more
openalex +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
TLÖN, UQBAR, ORBIS TERTIUS AND POSSİBLE WORLD(S)
Zeitschrift für die Welt der Türken, 2011 Borges is fond of speculating upon the very nature of reality and his metafictional strategies first invert and then undermine ontological certainty.
Fikret Mehmet ARARGÜÇ
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Možné svety, naratívna fikcia a autofikcia: odpoveď Petrovi Koťátkovi
Filosofický časopisThe aim of this article is to contribute to the discussion with Petr Koťátko about the nature of autobiographical and autofictional texts. It is argued that we approach all statements contained in an autofictional narrative text as readers in the as-if ...
Zouhar, Marián
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Possible worlds of a literary text character: a cognitive and quantitative linguistic approach
, 2021 Dmytro Pavkin
openalex +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
To think by building other possible worlds
, 2018 Alfonso Insuasty Rodríguez
openalex +2 more sources