Results 71 to 80 of about 1,723,317 (301)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

POSSIBLE SOLUTIONS TO THE WORLD CRISIS. AN ACCOUNTING PERSPECTIVE [PDF]

open access: yesCES Working Papers, 2010
Purpose – Our aim is to seize the essential aspects of the economical-financial environment and the alternatives that the companies have in their confrontation with the current challenges, the reorganization of the company being regarded as an option for
Daniela Ciotină, Cristina-Ionela Fădur
doaj  

Des mots et des jeux

open access: yesSciences du Jeu, 2019
The present King of France and Sherlock Holmes are classically referred to by analytic philosophy, bringing their puzzles into philosophy of language and philosophy of mind.
Manuel Rebuschi
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Obesity in Children in the Modern World: Realities and Possible Solutions

open access: yesВопросы современной педиатрии, 2016
The article presents data on the prevalence of obesity in children in the modern world, addresses the issues of etiology, pathogenesis, prevention, and treatment of the disease.
Anvar A. Dzhumagaziev   +7 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

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