Results 41 to 50 of about 16,273 (298)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
O artigo discute as tensões desencadeadas no pós-abolição em pequenas cidades do Vale do Paraíba Paulista, tais como São José dos Campos, Jacareí e Paraibuna.
Maria Aparecida Chaves Ribeiro Papali +2 more
doaj +1 more source
The theatrical trilogy Le Monde incréé offers a condensed vision of Édouard Glissant’s conception of the post-Columbian world. The latter, shaped through the tremendous violence of exterminations, slavery, and colonial expansion, is marked by a ...
Christian Uwe
doaj +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
This article aims to outline an overview of maroon communities existing in São Paulo, from the sixteenth century to the present day. In order to do so, the article examines various documental and bibliographical sources in search of clues that can enable
Flávio dos Santos Gomes +1 more
doaj +1 more source
The Swahili Art of Indian Taarab: A Poetics of Vocality and Ethnicity on the Kenyan Coast [PDF]
Employing approaches from ethnomusicology and vocal anthropology, Eisenberg undertakes an interpretive-ethnographic analysis of Indian taarab, a genre of Swahili song on the Kenyan coast that features Swahili words set to Hindi film song melodies ...
Andrew Eisenberg
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Le Massacre des affranchis. Race, émancipation et la République de 1889 à São Luís
This article deals with the circumstances that led to the shooting of the so-called « freed black monarchists » on November 17, 1889, in the city of São Luís do Maranhão. The conflict, still in need of comprehensive historical analysis, resulted from the
Matheus Gato
doaj
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

