Results 51 to 60 of about 16,273 (298)

Após o treze de maio: A convivência entre afro-descendentes e imigrantes em São Paulo nas primeiras décadas do século XX

open access: yesMediações: Revista de Ciências Sociais, 2002
In this article we are going to analyse some life experiences of "paulistas" afro-descendants developed in the urban area during the post abolition period.
Lúcia Helena Oliveira Silva
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Rethinking Carceral Domesticity. Electronic Monitoring, Punishment and Home as Prison [PDF]

open access: yesPad, 2023
This article explores the evolving dynamics of carceral domesticity in the context of Electronic Monitoring (EM) as a contemporary techno-penal practice.
Ece Canlı
doaj  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Malaysia’s death penalty: a post-abolition research agenda

open access: yesGlobal Social Challenges Journal
Malaysia’s landmark 2023 decision to abolish the mandatory death penalty – thus granting judges discretion over 12 capital offences – marks a pivotal shift, significantly reducing the death row population from over 1,300 to approximately 140 by late 2024.
Nasrul Ismail
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Ethnicity and labour in Mauritius: assessing a cinematic account [PDF]

open access: yes, 2016
We assess the sole substantial film documenting the history of socio-economic relations in Mauritius, a history stamped by long experiences of slavery and bonded labour.
Croucher, Richard, Houssart, Mark
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Ringue ou academia? A emergência dos estilos modernos da capoeira e seu contexto global [Capoeira circle or sports academy? The emergence of modern styles of capoeira and their global context] [PDF]

open access: yes, 2013
The emergence of the modern styles of capoeira should be considered in the global context of the modernization of martial arts currently in progress in Europe and Asia on the one hand, and the new phase of Afro-descendant modernity on the other.
Röhrig Assunção, Matthias
core   +2 more sources

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