Results 121 to 130 of about 11,707,023 (237)

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

Health Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha, Moubani Dutta, Agnihiya Bosu   +2 more
wiley   +1 more source

Speech, Language and Swallowing Disorders in the Symptomatology of Post-COVID-19 Syndrome

COVID-19 is a highly contagious disease caused by the SARS-CoV-2 coronavirus, and its pandemic has gradually affected the entire world. While most symptoms of this disease disappear during the acute phase, some symptoms may persist for several months ...
Simona Hlaváčová
core   +1 more source

Pursuing Leadership on One's Own Terms: A Human Resource Development Perspective on Leadership Aspiration, Identity, and Organizational Influence

Human Resource Development Quarterly, EarlyView.
ABSTRACT Leadership aspiration is not simply a product of ambition or capability, but a dynamic, context‐sensitive phenomenon shaped by how individuals understand leadership and whether pursuing it feels feasible, meaningful, and sustainable. Using phenomenographic analysis of semi‐structured interviews with 23 employees and drawing on Leadership ...
Bishakha Mazumdar, Stephanie Gilbert, Megan M. Walsh   +2 more
wiley   +1 more source

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad, Francesc Balaguer, Elizabeth E. Half, Kevin J. Monahan, Elena M. Stoffel, Sonia S. Kupfer   +5 more
wiley   +1 more source

Pain at intrauterine device placement in a Brazilian center

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study explores pain at intrauterine device (IUD) placement in a large Brazilian cohort. Methods We undertook a cross‐sectional analysis of health records from individuals aged 18 to 45 years who underwent IUD placements between 2022 and 2024 at the Department of Obstetrics and Gynecology, Universidade Estadual de Campinas ...
Ana Luiza Savi, Judith Lieber, Cássia Raquel Teatin Juliato, Rachel Scott, Luis Bahamondes   +4 more
wiley   +1 more source

Post-COVID-19 condition symptoms among emergency department patients tested for SARS-CoV-2 infection

Nature Communications
Symptoms of the Post-COVID-19 Condition are often non-specific making it a challenge to distinguish them from symptoms due to other medical conditions.
Patrick M. Archambault, Rhonda J. Rosychuk, Martyne Audet, Jeffrey P. Hau, Lorraine Graves, Simon Décary, Jeffrey J. Perry, Steven C. Brooks, Laurie J. Morrison, Raoul Daoust, David Seonguk Yeom, Hana Wiemer, Patrick T. Fok, Andrew D. McRae, Kavish Chandra, Michelle E. Kho, Dawn Stacey, Bilkis Vissandjée, Matthew Menear, Eric Mercier, Samuel Vaillancourt, Samina Aziz, Dianne Zakaria, Phil Davis, Katie N. Dainty, Jean-Sébastien Paquette, Murdoch Leeies, Susie Goulding, Elyse Berger Pelletier, Corinne M. Hohl, Canadian COVID−19 Emergency Department Rapid Response Network (CCEDRRN) investigators, Network of Canadian Emergency Researchers, Canadian Critical Care Trials Group investigators   +32 more
doaj   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Unfractionated Heparin and Low‐Molecular‐Weight Heparin in Sepsis: Anti‐Inflammatory and Anticoagulant Effects Versus No Anticoagulation—A Propensity Score‐Matched Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
This propensity score‐matched study compared unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) in 1362 sepsis patients, finding that both significantly improved survival without increasing 90‐day bleeding risk. However, their therapeutic mechanisms differed: UFH demonstrated broader anti‐inflammatory effects by reducing IL‐6, IL‐8 ...
Peili Chen, Yi Yao, Bing Zhao, Yuan An, Jian Jiang, Li Ma, Enqiang Mao, Yihui Wang   +7 more
wiley   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Medical trauma in context: Recognizing and addressing medically induced posttraumatic stress disorder in adults

Journal of Traumatic Stress, EarlyView.
Abstract Potentially traumatic medical events (PTMEs) occur across acute and chronic illness trajectories, such as invasive procedures, intensive care, and life‐threatening diagnoses. Emerging evidence suggests that approximately 20% of individuals exposed to PTMEs develop posttraumatic stress disorder (PTSD).
Reneé El‐Gabalawy, Sarah A. Stoycos, Nicholas Schumann, Keisha‐Gaye N. O'Garo, Sacha McBain   +4 more
wiley   +1 more source