Results 81 to 90 of about 223,105 (281)

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Post COVID-19 syndrome and new onset diseases: a prospective observational study

Singapore Medical Journal
Introduction: The National Institute of Health and Care Excellence (NICE) has defined the terms, ‘acute coronavirus disease 2019’ (COVID-19), ‘ongoing symptomatic COVID-19’ and ‘post-COVID-19 syndrome’, with the latter two described as having persistent ...
Nitin Sinha, Mahinder Pal Singh Chawla, Desh Deepak, Amit Suri, Piyush Jain, Ankit Agarwal, Manoj Kumar Bhakhar   +6 more
doaj   +1 more source

Post-COVID Syndrome: An Insight on Its Pathogenesis

, 2021
Post-COVID syndrome is increasingly recognized as a new clinical entity in the context of SARS-CoV-2 infection. Symptoms persisting for more than three weeks after the diagnosis of COVID-19 characterize the post-COVID syndrome.
Helena C. Maltezou, Androula Pavli, Athanasios Tsakris   +2 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Role of gut microbiota in acute COVID-19 and post-acute COVID-19 syndrome

Microbiota in Health and Disease, 2022
Coronavirus disease-2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mostly affects the respiratory system but emerging data showed that the human gut is also involved. Microbes in the gut play crucial roles in maintaining immune regulation and metabolic homeostasis. The imbalance of the gut microbiota composition,
Liu, Q., Su, Q., Lau, R. I., Zhang, F., Chan, F. K.L., Ng, S. C.   +5 more
openaire   +1 more source

Pre-COVID-19 physical activity status does not protect against reductions in post-covid-19 symptoms: a correlation relativistic analysis during the lockdown [PDF]

, 2023
People who exhibit unhealthy lifestyle behaviours are at greater risk of severe disease outcomes, risk of hospitalisation and mortality when infected with COVID-19.
Ashton, R., Ferraro, F., Faghy, M., Owen, R.   +3 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Post-COVID Syndrome in Adults—An Overview

, 2023
This article provides an overview of various aspects related to post-COVID syndrome. Apart from its prevalence, symptoms and sequelae, risk determinants, and psychosocial implications, the pathogenesis of post-COVID condition is discussed in more detail.
Juan-Manuel Anaya, Rüdiger E. Scharf
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Post COVID-19: a narrative review of a new challenge

Sri Lanka Journal of Medicine, 2021
COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Though the majority of the patients infected with COVID-19 fully recover, persistent illness and symptoms have been identified among a considerable number of patients ...
L. Kaushalya, G. Bowatte, D. Yasaratne
doaj   +1 more source