Results 121 to 130 of about 88,947 (253)

Dual Physiological Barriers Bypassed by a Silk‐Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease

Advanced Science, EarlyView.
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu, Tiandong Li, Jian He, Yujian Jiang, Yeyuan Wang, Jingchen Sun   +5 more
wiley   +1 more source

A nomogram to predict hypoxemia in the post-anesthesia care unit after laparoscopic bariatric surgery. [PDF]

BMC Anesthesiol
Wang M, Li Y, Gong Q, Xu Y, Chen X, Fan J.   +5 more
europepmc   +1 more source

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Analysis of Factors Influencing Extended Post Anesthesia Care Unit Length of Stay (PACU-LOS) in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy. [PDF]

Obes Surg
Zhang X, Wei B, Zhang J, Guo X, Li M.
europepmc   +1 more source

The construction of patient quality management model in oral post anesthesia care unit in China: a grounded theory approach. [PDF]

BMC Anesthesiol, 2023
Zhang Q, Tang H, Yao Z, Han W.
europepmc   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Rapidly Progressive Subcutaneous Emphysema and Sequential Bilateral Pneumothoraces Following Pediatric Tracheocutaneous Fistula Closure: A Postoperative Air-Leak Syndrome Recognized in the Post-anesthesia Care Unit (PACU). [PDF]

Cureus
Bryant D, Pius A, Choromanski D.
europepmc   +1 more source

Extracorporeal membrane oxygenation as acute rescue therapy for negative pressure pulmonary edema in the post anesthesia care unit: A case report. [PDF]

Clin Case Rep, 2023
Augustin KJ, Creel-Bulos CM, Budhrani GF, Miller CF, Fiza B.   +4 more
europepmc   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Prevalence and Risk Factors for Prolonged Post Anesthesia Care Unit Stay among Adults at a Referral Hospital in Kigali, Rwanda. [PDF]

Rwanda J Med Health Sci
Yamuragiye A, Ikitegetse E, Mugisha EN, Niyitegeka JP.   +3 more
europepmc   +1 more source