Results 141 to 150 of about 89,630 (255)

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

Incidence and factors associated with post-anesthesia care unit complications in resource-limited settings: An observational study. [PDF]

Health Sci Rep, 2022
Abebe B, Kifle N, Gunta M, Tantu T, Wondwosen M, Zewdu D.   +5 more
europepmc   +1 more source

Pain management of patients in post anesthesia care unit [PDF]

Journal of PeriAnesthesia Nursing, 2004
Herminia Robles, Pamela E Windle, Rebecca Krepper, Jackie Anderson   +3 more
openaire   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Effect of preoperative patient education and simulated mouth breathing training on opioid requirements in the post-anesthesia care unit after nasal surgery: a randomized controlled study. [PDF]

BMC Anesthesiol, 2023
Bang YJ, Kim S, Kim JK, Kim H, Kim S, Chung CS, Yoo SY, Jeong H, Park B, Lee SH.   +9 more
europepmc   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Family presence in post-anesthesia care unit reduces negative postoperative behavioral changes in preschool children: a randomized controlled trial. [PDF]

Am J Transl Res
Zhang YR, Liu AH, Wan YY, Wang QQ, Chen DD, Zhuang PJ, Mo YQ.   +6 more
europepmc   +1 more source

The Assessment of Immediate Postoperative Delirium in Neurologically Intact Adult Patients Admitted to the Post-anesthesia Care Unit: A Cross-Sectional Study. [PDF]

Cureus, 2022
Burad J, Date R, Al Ismaili M, Sharma P, Kuriakose N, Kodange S, Birur SK, Al Yaqoubi K, Al Mawali A, Padmalayan A, El Mady H, Elawdy M, Jaju S, Al Abady A.   +13 more
europepmc   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Specifying the Objectives and Techniques of a Competency-based Training Program to Improve Post-anesthesia Care Unit Nurse Performance: A Delphi Study. [PDF]

Iran J Nurs Midwifery Res
Khalafi A, Behzadi M, Sarvi-Sarmeydani N, Saidkhani V.   +3 more
europepmc   +1 more source