Results 71 to 80 of about 89,630 (255)

Cotimparave Evaluation of Oral Alprazolam, as Premedication, on Controlling Blood Pressure in Hypertensive Patients during Surgery

open access: yesمجله دانشکده پزشکی اصفهان, 2015
Background: One of the major challenges in adult surgery is hypertension. Hypertensive patient are in danger of  myocardial ischemia, increasing blood pressure in recovery room, kidney injury and cerebral artery damage.
Parvin Sajedi, Mortaza Rezaie
doaj  

Incidence of hypoxemia in a post-anesthesia care unit and relevant risk factors [PDF]

open access: yesJichu yixue yu linchuang, 2020
Objective To investigate the incidence and potential risk factors of postoperative hypoxemia in a post-anesthesia care unit (PACU). Methods The retrospective cohort assessed 14 604 postoperative patients who were admitted to PACU in a period of one ...
ZHANG Liang-yan, TANG Shuai, ZHANG Xiu-hua, HAN Wei, XUE Yang, TIAN Yi, HUANG Yu-guang
doaj  

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang   +6 more
wiley   +1 more source

Management of Anesthesia in Pediatric Patients with Bronchoscopy Late Onset Foreign Body Aspiration

open access: yesIndonesian Journal of Anesthesiology and Reanimation (IJAR)
Introduction: Aspiration of foreign bodies in the airways is a severe and fatal condition if it occurs in children, because the risk of life-threatening obstruction is higher.
Rinni Sintani, Rudy Vitraludyono
doaj   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

open access: yesAdvanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao   +18 more
wiley   +1 more source

A visualization analysis of research on arterial compression hemostatic devices using VOSviewer and CiteSpace

open access: yesFrontiers in Neurology
BackgroundCardiovascular and cerebrovascular diseases pose a significant health challenge in modern society, with the advancement of interventional therapy and vascular intervention technology playing crucial roles.
Li Liu   +5 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

open access: yesAdvanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie   +12 more
wiley   +1 more source

Rectus sheath block as the sole anesthesia technique for open surgical repair of umbilical hernias: A retrospective cohort study

open access: yesSaudi Journal of Anaesthesia
Background: The rectus sheath block is a regional anesthetic technique that provides effective analgesia for midline abdominal surgeries. This study evaluated the feasibility of the rectus sheath block as the sole anesthetic technique for open umbilical ...
Emma L. Rispler   +5 more
doaj   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang   +10 more
wiley   +1 more source

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