Results 21 to 30 of about 5,184,324 (291)

Politics, Penality and (Post-)Colonialism [PDF]

open access: yesCultural and Social History, 2008
(2008). Politics, Penality and (Post-)Colonialism. Cultural and Social History: Vol. 5, No. 4, pp. 391-394.
Alexander, Jocelyn, Anderson, Clare
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Rethinking the toponymic politics in Belarus in the 20–21 centuries: toward the post-colonial perspective

open access: yesJournal of Geography, Politics and Society, 2020
The article explores the historical trends and patterns in the politics of space in toponymic landscapes of Soviet and postSoviet Belarus through the prism of critical toponymy and the post-colonial theoretical approach.
Sergei Basik
doaj   +1 more source

Mallaby’s car: colonial subjects, imperial actors, and the representation of human suffering in postcolonial exhibitions [PDF]

open access: yesThe Open Arts Journal, 2014
The iconic photograph of Mallaby’s car shows the wreckage of the vehicle of British brigadier A.S. Mallaby, which was destroyed in Surabaya in Indonesia on 30 October 1945 during the Indonesian uprising against the restoration of Dutch colonial rule. The
Susan Legêne
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

RICE IN COLONIAL AND POST COLONIAL SOUTHEAST ASIA: A FOOD REGIME ANALYSIS

open access: yesParamita: Historical Studies Journal, 2015
This paper traces the ways in which rice, as a global commodity, has been produced and sold in various regions in Southeast Asia from the colonial era to the present days.
Dias Pradadimara
doaj   +1 more source

Proud to be a Goan: colonial memories, post-colonial identities and music [PDF]

open access: yes, 2010
During 451 years of colonial history, catholic Goans used music as a mediator of identity negotiation. In a political context repressing musical sonority of Indian flavour, in which Portuguese was the official language, catholic Goans created their own ...
Sardo, Susana
core  

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