Results 41 to 50 of about 5,184,324 (291)

Knocking, Unsettling, Ceding

open access: yesNordic Journal of Comparative and International Education, 2020
This paper explores a reflexive decolonizing framework, arising from a teachers` first four years of teaching practice in an Indigenous community in the North of what is commonly known as Australia[A1].
Jessica Gannaway
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Silenced languages: Probing biblical texts and South African context post-colonially

open access: yesTheologia Viatorum
he marginalisation of languages by colonial and apartheid structures distorted cultural identities, obstructing the power and independence of various communities.
Mlamli Diko
doaj   +1 more source

The Challenge of Language and Cultural Identity in Post-Colonial Africa’s National Economic Development [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2021
Except for a few, most countries particularly African nations that transited from colonial rule to self-governance have imbibed and internalized the language and culture of the colonial overloads across the broad spectrum and tapestry of their social ...
Gideon Simon Ghajiga   +1 more
doaj  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Fiqh Siyasah in Indonesia’s Post-colonial Era: Between Classical Doctrines and Contemporary Practices

open access: yesel-Aqwal
This study examines contemporary understandings of Fiqh Siyasah—a branch of Islamic legal thought concerned with governance and political relations—within Islamist movements in post-Reformasi Indonesia.
Bani Syarif Maula
doaj   +1 more source

Carnival as Contentious Performance

open access: yesJournal of Festive Studies, 2020
In the 1970s, in a context of increased racial tensions and growing nationalist claims, the use of rhythms, instruments, and clothing associated with Africa among the black populations of England, Guadeloupe, and Martinique became part of a cultural and ...
Lionel Arnaud
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Rhythm, contagion, "cosmic race”

open access: yesFedro
In his text Pitágoras. Una teoría del ritmo (1921), the Mexican philosopher José Vasconcelos carries out an interesting rereading of ancient Pythagoreanism to reorient the symbolic-abstract direction of Western thought, which seems to pave a new line of
Lorena Grigoletto
doaj   +1 more source

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