Results 131 to 140 of about 1,548,359 (310)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Post-Conflict Reconstruction: The Changes in Relations between Government and Non-Governmental Organizations

Czech Journal of International Relations, 2008
Non-governmental organizations participate more than two decades on post-conflict reconstruction and peace-building. They participated on reconstruction of Bosnia and Herzegovina, Angola and Haiti.
Šárka Waisová
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Trauma Rehabilitation after War and Conflict

Politikon, 2015
Adela Militaru
doaj   +1 more source

Policies towards Horizontal Inequalities in Post-Conflict Reconstruction [PDF]

inequality, conflict, reconstruction ...
Stewart, Frances
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Post-conflict acute stress reactions in Kazakhstan in the aftermath of January 2022 unrests: A national survey. [PDF]

Heliyon, 2023
Glushkova N, Ivankov A, Trenina V, Oshibayeva A, Kalmatayeva Z, Temirbekova Z, Mamyrbekova S, Davletov K, Khismetova Z, Kauysheva A, Auyezova A, Zhanaspayev M, Pivina L, Koshmaganbetova G, Nurbakyt A, Sarsenbayeva G, Sadibekova Z, Gazaliyeva M, Kulimbet M, Kalmatayeva D, Zhylkybekova A, Nurgaliyeva Z, Sultanbekov K, Semenov D, Izmailovich M, Tsigengagel O, Munir K.   +26 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Third-party intervention and post-conflict behaviour in agonistic encounters of pigs (Sus scrofa). [PDF]

Front Zool, 2023
Maffezzini N, Turner SP, Bolhuis JE, Arnott G, Camerlink I.   +4 more
europepmc   +1 more source

Aid Effectiveness and Selectivity: Integrating Multiple Objectives into Aid Allocations [PDF]

aid, growth, policy, selectivity, poverty reduction, post-conflict, democracy, political stability, economic ...
McGillivray, Mark
core