Results 201 to 210 of about 271,434 (255)

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Conservative Management of Negative Pressure Pulmonary Edema: A Case Report. [PDF]

Cureus
Jagadish A, Ross JM, Gibson B.
europepmc   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Efficacy and Safety of Reteplase Versus Alteplase in Acute Ischemic Stroke Based on Fibrinogen Levels: The RAISE Trial Subgroup. [PDF]

J Am Heart Assoc
Wang J, He D, Gu H, Li Z, Wang Y, Zhao X, Wang Y, Li S.   +7 more
europepmc   +1 more source

The crossroad of delirium, mania, and catatonia: A case series on delirious mania. [PDF]

Indian J Psychiatry
Gangwal R, Nawale VS, Mudgal V, Mathur R.   +3 more
europepmc   +1 more source

Disability and Post-dramatic Theater: Return of Storytelling

Journal of Literary and Cultural Disability Studies
openaire   +1 more source

Reply : Efficacy of intracameral moxifloxacin in prevention of post-cataract surgery endophthalmitis: a randomized controlled trial. [PDF]

J Cataract Refract Surg
Sharma N, Sen A, Sharma M, Bari A, Bari A, Shakkarwal C, Maharana PK, Agarwal T, Dada T, Gaur S, Joshi R, Das SA, Upadhyay AD, Titiyal JS.   +13 more
europepmc   +1 more source

3D-Printed Bolus-Assisted Radiotherapy for Converting Unresectable Breast Cancer with a Breast Prosthesis into a Resectable Condition: A Case Report. [PDF]

Curr Oncol
Hung SK, Tsai WT, Lin CH, Lee MS, Lin HY, Chen LC, Chew CH, Hsu FC, Chiou WY.   +8 more
europepmc   +1 more source

Psychedelics, the media portrayal and large-language model evaluations. [PDF]

BJPsych Open
Clelland CL.
europepmc   +1 more source

A Post-Dramatic Analysis of Simon Stephens's Play: The Curious Incident of the Dog in the Night-Time

مجلة البحث العلمي في الآداب
openaire   +1 more source