Results 91 to 100 of about 4,345,916 (315)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Herbicide Screening and Application Method Development for Sustainable Weed Management in Tagetes erecta L. Fields

Plants
Marigold (Tagetes erecta L.), a crop of significant medicinal, ornamental, and economic value, faces severe industrialization challenges due to weed-induced yield losses (up to 60%).
Yiping Zhang, Dongyan Feng, Chengcheng Jia, Wangqi Huang, Feng Xu, Yalian Jiang, Junhong Huang, Ye Li, Jihua Wang, Dongsheng Tang   +9 more
doaj   +1 more source

Impact of a new post-emergency teleconsultation procedure on overcrowding

DIGITAL HEALTH
Background Saint Vincent de Paul Hospital is using a post-emergency teleconsultation solution (TELESCOPE). Target patients are discharged early, freeing up examination rooms and hospital beds, and the patient's clinical evolution is monitored by teleconsultation 24 hours after discharge.
Chavda, Emmanuelle, Norberciak, L., Guedon Moreau, Laurence, Casalino, E., Williatte, L., Wiel, Eric, Thellier, N., Cordova, Enrique   +7 more
openaire   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Response of Wheat to Pre-Emergence and Early Post-Emergence Herbicides

Agronomy
A two-year field experiment was conducted in two consecutive seasons to evaluate the response of wheat to pre-emergence (PRE) and early post-emergence (EPOST) herbicides.
Thomas Gitsopoulos, Ioannis Georgoulas, Despoina Botsoglou, Eirini Vazanelli   +3 more
doaj   +1 more source

Potential of Vochysia divergens extracts as a post-emergence bioherbicide

Brazilian Journal of Biology
Abstract The genus Vochysia, particularly Vochysia divergens Pohl, has been studied for its diverse biological activities and phytochemical composition. This study investigates the phytotoxic potential of V. divergens extracts as bioherbicides, with emphasis on their effects on photosystem II (PSII) and weed growth.
R. de Almeida, L. C. C. Vieira, M. C. M. Sales, G. P. Nishino, A. Ali, B. S. Bellete, M. A. Silva, O. M. Sampaio   +7 more
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Food Consumption Behavior in Bandung Post COVID-19 Pandemic Emergence

Journal of Management and Business Review
This research was done to discern changes in food consumption behavior in Indonesia two years after the emergence of the COVID-19 pandemic. Primary data for this research was gathered through questionnaires distributed from 26 June 2022 until 26 July ...
Yosephine Carolina Nugraha, Sabrina Wissen, Shafira Putri Kurniawan   +2 more
doaj   +1 more source

Emergency and post-emergency situations Educational and teaching model

Ricerche di Pedagogia e Didattica, 2013
Ricerche di Pedagogia e Didattica. Journal of Theories and Research in Education, Vol 8, No 2 (2013)
openaire   +3 more sources