Results 101 to 110 of about 4,345,916 (315)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The Nature of the Transformation in Transformational Emergence
, 2018 Discussion about the nature of the transformation in the case of transformational ...
Guay, Alexandre, Diachronic Emergence
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ONTOLOGY, MATTER AND EMERGENCE [PDF]
, 2007 “Ontological emergence” of inherent high-level properties with causal powers is witnessed nowhere. A non-substantialist conception of emergence works much better.
Bitbol, Michel, Michel, Bitbol
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
, 2007 Fiscal year ends June 30.; "November 20, 2007."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The effect of different herbicides and soil moisture regimes on Camelina performance
Acta Biologica SlovenicaThis experiment aimed to evaluate the effect of different herbicides, including H0: no application of herbicide, H1: trifluralin as a pre-emergence herbicide, H2: cycloxydim, H3: haloxyfop-R-methyl, and H4: pinoxaden as post-emergence herbicides, on ...
Asghar Ebadi-Segherloo +3 more
doaj +1 more source
Citronella essential oil-based nanoemulsion as a post-emergence natural herbicide. [PDF]
Sci Rep, 2023 Somala N +3 more
europepmc +1 more source
, 2005 Fiscal year ends June 30.; "November 1, 2005."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source