Results 21 to 30 of about 65,817 (260)

Implementation and impact of a post-exposure prophylaxis helpline [PDF]

Occupational Medicine, 2015
Despite a 2007 national and regional training programme, there was poor implementation of a post-exposure prophylaxis (PEP) programme to prevent occupational transmission of HIV in health care workers (HCWs) in Delhi. A new initiative was therefore launched by the Delhi State AIDS Control Society in 2010 to improve uptake of PEP in HCWs.To assess the ...
A K, Gupta, A C, Gupta, A, Gupta, S S, Ranga, B B, Rewari, A P, Bansal   +5 more
openaire   +2 more sources

Exposure to hepatitis B virus, post-exposure prophylaxis knowledge, and related factors among healthcare workers in a tertiary care military facility in Ghana: A cross-sectional analytical study

Scientific African
Background: Healthcare workers are at increased risk of exposure to hepatitis B virus due to occupational hazards. Adequate knowledge and adherence to post-exposure prophylaxis protocols are crucial in minimizing HBV transmission.
Berlinda Lasidji Narh, Vivian Efua Senoo-Dogbey, Monica Charlotte Akpagloh   +2 more
doaj   +1 more source

Exposure to Biological Fluids in Dental Practice—Narrative Review on Appropriate Risk Assessment to Guide Post-Exposure Management

Pathogens, 2023
Accidental exposure to blood or other biological fluids is a common occurrence in dentistry, and its post-exposure management is a key component of infection prevention and control programs designed to prevent the transmission of blood-borne pathogens ...
Mihai Săndulescu, Mihnea Ioan Nicolescu, Cristian Funieru, Gülşen Özkaya Şahin, Oana Săndulescu   +4 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Changes in HIV post-exposure prophylaxis prescriptions before and after the introduction of HIV pre-exposure prophylaxis at a sexual health clinic in Melbourne, Australia, 2011–2021

Australian and New Zealand Journal of Public Health
Objective: HIV pre-exposure prophylaxis (PrEP) became available in Victoria, Australia, in 2016. We examined non-occupational post-exposure prophylaxis (nPEP) usage among gay, bisexual and other men who have sex with men (MSM) before and after PrEP ...
Ranjit S. Samra, Christopher K. Fairley, Jason J. Ong, Ei T. Aung, Eric PF. Chow   +4 more
doaj   +1 more source

Remediated sexuality: the meanings of postand pre-exposure prophylaxis for HIV [PDF]

Saúde e Sociedade
This article discusses the sexual character of HIV preand post-exposure prophylaxis (PEP and PrEP, respectively). It derives from a socio-anthropological study on the biomedicalization of responses to HIV that analyzed the offer of these prophylaxes in ...
Mauro Brigeiro, Simone Monteiro
doaj   +1 more source

Exploring Pre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP) Knowledge in Incarcerated Men

American Journal of Men's Health, 2022
People who are incarcerated have a disproportionately high risk of contracting human immunodeficiency virus (HIV). While there is no known cure for HIV, there are biomedical approaches that can successfully manage the virus and prevent its transmission ...
Pamela Valera, Zaire S. Ali, Diamond Cunningham, Christopher McLaughlin, Sebastian Acevedo   +4 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source