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The post-finasteride syndrome: possible etiological mechanisms and symptoms

International Journal of Impotence Research, 2023
Finasteride and dutasteride, synthetic 5α-reductase inhibitors (5ARIs) are recommended in many guidelines for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms and alopecia despite a variety of side effects like sexual, neurological, psychiatric, endocrinological, metabolic and ophthalmological dysfunctions and the increased ...
Herman H. J. Leliefeld   +2 more
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Das Post-Finasterid-Syndrom

Gynäkologische Endokrinologie, 2017
Das Post-Finasterid-Syndrom (PFS) beschreibt eine langfristige Storung der Sexualfunktion sowie psychische und kognitive Veranderungen, die wahrend oder nach der Behandlung einer androgenetischen Alopezie (AGA) mit 1 mg Finasterid pro Tag bzw. wahrend oder nach der Therapie einer benignen Prostatahyperplasie (BPH) mit 5 mg/Tag auftreten und nach ...
Herbert Kuhl, Inka Wiegratz
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Trazodone associated with Clomiphene a proposal treatment for post finasteride syndrome

Magna Scientia Advanced Research and Reviews, 2023
Erectile dysfunction caused by medications are probably caused by the disconnection of synaptic circuits responsible for linking libido to erection. For instance, it is well known that sexual dysfunction may occur in patients treated with finasteride, an inhibitor of the enzyme 5alpha-reductase, prescribed for androgenetic alopecia and benign prostatic
openaire   +1 more source

(122) Erectile Hemodynamics Asessment In ED Patients With Self-Diagnosed Post-finasteride syndrome (PFS)

The Journal of Sexual Medicine, 2023
Abstract Introduction Much debate exists regarding the concept of PFS and its etiology. There exists data suggesting abnormal erectile hemodynamic alterations in this population. Objective This analysis was performed to define ...
S Deveci   +3 more
openaire   +1 more source

Post-finasteride syndrome - a true clinical entity?

International Journal of Impotence Research
This review critically examines Post-Finasteride Syndrome (PFS), a condition eventually reported by men who have used finasteride for androgenetic alopecia or benign prostatic enlargement and experienced persistent adverse effects after discontinuation. We explore the clinical manifestations, including sexual dysfunction, neuropsychiatric symptoms, and
Simone Cilio   +4 more
openaire   +2 more sources

Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin?

Endocrine, 2018
Sexual dysfunction is a clinical condition due to different causes including the iatrogenic origin. For instance, it is well known that sexual dysfunction may occur in patients treated with antidepressants like selective serotonin reuptake inhibitors (SSRI). A similar side effect has been also reported during treatment with finasteride, an inhibitor of
Silvia Giatti   +3 more
openaire   +2 more sources

Epigenetic Effects of Finasteride on Dopaminergic Signaling Pathways: A potential contributor to Post-Finasteride Syndrome

Physiology
Dopamine, a widely-distributed neurotransmitter in the brain and elsewhere, is important for regulating reward-motivated behavior, sexual impetus, concentration, pleasure, emotions, and genital arousal. Findings have previously implicated aberrant dopaminergic neurotransmission in mental disorders, as well as sexual and erectile dysfunction.
Churchill J Ihentuge, Antonei B Csoka
openaire   +1 more source

(135) Post-Finasteride Syndrome: A Case Presentation and Discussion

Journal of the Academy of Consultation-Liaison Psychiatry, 2022
Daniel Wesley, Rachel Bronsther
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