Results 31 to 40 of about 545,904 (303)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
ASTHENIC SYNDROME IN THE PEDIATRICIAN PRACTICE
Медицинский совет, 2016 Asthenia (from Greek σθένεια impotence) is a pathological condition characterized by weakness, fatigability, emotional lability, hyperesthesia, sleep disorders.
I. N. Zaharova +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A rapid product development environment for post-graduate student aircraft design projects [PDF]
, 2005 Post-graduate education in aircraft design needs to prepare students for their future roles as professional engineers in the aerospace industry. A key requirement from industry is for students to learn how to deal with realistic open ended design ...
Fielding, John, Lockett, Helen L.
core
VITAMIN D INSUFFICIENCY: WHAT’S NEW?
Вопросы современной педиатрии, 2014 Currently, scientists are continuing discussions on the definition of the precise level of vitamin D in the blood serum, but there is a consensus that vitamin D insufficiency is common throughout the world and has an adverse effect on human health.
I. N. Zakharova +3 more
doaj +1 more source
LEVELS OF SYSTEMIC INFLAMMATORY RESPONSE MARKERS IN PATIENTS WITH PULMONARY HYPERTENSION AND COPD
Східноукраїнський медичний журнал, 2020 Introduction. The prevalence of COPD worldwide is about 7.6 %, and it is one of the main causes of morbidity and mortality in today society. Today, much information has been obtained about the pathogenetic mechanisms of COPD development.
I. M. Fushtey +2 more
doaj +1 more source
Kounis syndrome secondary to nimesulide ingestion: a case report
The Egyptian Heart Journal, 2021 Background Kounis syndrome, also known as "allergic myocardial infarction," is a rare co-occurrence of acute coronary syndrome (ACS) in the setting of hypersensitivity reaction to any agent.
Yamasandi Siddegowda Shrimanth +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Derrida, Butler and an Education in Otherness [PDF]
, 2009 Proceedings of the 2nd International Colloquium between the Graduate School of Education, Kyoto University (Japan) and the Institute of Education, University of London (UK) : 28 February- 1 March 2009 Kyodai Kaikan Kyoto ...
Ian Munday, Munday, Ian
core
Post-school Transitions of People who are Deaf or Hard of Hearing:Final Report [PDF]
, 2013 The ongoing UK and European economic crisis is leading to a rapid growth in youth unemployment in Scotland. Young disabled people, including those who are deaf or hard of hearing, are more likely than others to experience difficulties in obtaining ...
O'Neill, Rachel; id_orcid +3 more
core +1 more source