Results 31 to 40 of about 193,000 (260)

Finding an Alternative for the Surgical Clips-based Delineation of Tumor Bed Boost Volume for Radiotherapy after Breast Conserving Surgery: A Prospective Comparative Study

Asian Pacific Journal of Cancer Care, 2021
Background: Radiotherapy after breast conserving surgery includes irradiation of whole breast and regional lymphatic areas which is followed by a boost to the tumor bed.
Mrutyunjayarao Muvvala, Pragna Sagar Rapole, Gunaseelan Karunanithi, Vijayaprabhu Neelakandan, Kadambari Dharanipragada   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Outcomes of OCT imaging-based reoperations in strabismus

BMC Ophthalmology
Purpose Reoperations in strabismus are reportedly needed in 20–40% of cases undergoing surgery. The present study investigated the outcomes of reoperations based on preoperative imaging of extraocular muscle insertions, and whether the Anterior Segment ...
Savleen Kaur, Jaspreet Sukhija, Srishti Raj, Shweta Chaurasia, Shubhi Singh M. Optom   +4 more
doaj   +1 more source

The effectiveness of writing techniques in improving students’ writing ability with different self-esteem

Studies in English Language and Education, 2022
Identifying appropriate writing techniques to help students with different self-esteem improve their writing ability needs to be considered by educators.
Ida Yulianawati, Mursid Saleh, Januarius Mujiyanto, Djoko Sutopo   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Feasibility and effectiveness of a hybrid teleaudiology model for accessible hearing healthcare: a mixed-methods study in Northern India

The Egyptian Journal of Otolaryngology
Background An estimated 63 million people in India have disabling hearing loss, yet access to hearing healthcare remains limited due to high costs, long travel distances, severe shortage of audiologists, and low awareness.
Md Noorain Alam, Sanjay Kumar Munjal, Sagrika Sharma, Jaimanti Bakshi, Naresh Kumar Panda   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Medical and biological functions of water

Фармацевтичний журнал, 2019
Water is the most common compound of hydrogen and oxygen in the nature. It is a universal solvent of many substances, and therefore chemically pure water does not exist in the nature.
R. S. Korytniuk, L. L. Davtian, N. I. Hudz, A. A. Drozdova, I. О. Vlasenko, M. V. Leleka, T. F. Olifirova   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source