Results 141 to 150 of about 12,754,412 (324)

Effect of Post Growth Annealing on the Structural and Electrical Properties of ZnO/CuO Composite Nanostructures

, 2013
In the present work, ZnO/CuO composite nanostructures have been grown on fluorine doped tin oxide coated glass substrate by aqueous chemical growth method.
Magnus Will, Hussain, Mushtaque, Willander, Magnus, Nur, Omer,, Omer Nur, Mushtaque Hussain, Khan, Azam,, Azam Khan, Khan, Azam, Hussain, Mushtaque,, Willander, Magnus,, Nur, Omer   +11 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Heart Rate Variability Biofeedback Training Can Improve Menopausal Symptoms and Psychological Well-Being in Women with a Diagnosis of Primary Breast Cancer: A Longitudinal Randomized Controlled Trial

Current Oncology
Breast cancer survivors experience numerous chronic symptoms linked to autonomic dysfunction including anxiety, stress, insomnia, menopausal symptoms, and cognitive impairment.
Karina Dolgilevica, Elizabeth Grunfeld, Nazanin Derakshan   +2 more
doaj   +1 more source

Sustainable agrifood systems for a post-growth world

Nature Sustainability, 2022
Steven R. McGreevy, Christoph D. D. Rupprecht, D. Niles, Arnim Wiek, M. Carolan, G. Kallis, K. Kantamaturapoj, A. Mangnus, P. Jehlička, Oliver Taherzadeh, M. Sahakian, I. Chabay, Ashley Colby, J. Vivero-Pol, R. Chaudhuri, M. Spiegelberg, Mai Kobayashi, B. Balázs, Kazuaki Tsuchiya, C. Nicholls, Keiko Tanaka, J. Vervoort, Motoki Akitsu, H. Mallee, Kazuhiko Ota, Rika Shinkai, Ashlesha Khadse, Norie Tamura, K. Abe, M. Altieri, Y. Satō, M. Tachikawa   +31 more
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Beyond growth in food systems: Cultivating seeds of change 

Journal of Political Ecology
The special issue Post-growth food systems for a just social-ecological transition within Planetary Boundaries explores post-growth and degrowth approaches that advocate for sufficiency, care, regeneration, and the democratization of food systems.
doaj   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Revisiting community-based traditional irrigation systems in India

Heliyon
Several scholars, policy think tanks and advocacy groups have advocated for reviving community-based traditional irrigation systems. Traditional irrigation systems are conceptualised as sustainable and resilient alternatives to large irrigation ...
Kumar Gaurav, Prabhakar Sharma, Aviram Sharma   +2 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source