Results 111 to 120 of about 2,839,497 (322)

On the use of post-hoc tests in environmental and biological sciences: A critical review

Heliyon
Post-hoc comparison procedures are commonly used to determine which group means differ after a significant analysis of variance (ANOVA). Several post-hoc tests have been proposed, but their use requires certain assumptions to be met, such as normality ...
Codjo Emile Agbangba, Edmond Sacla Aide, Hermann Honfo, Romain Glèlè Kakai   +3 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Benefit and Risks of Aspirin in Addition to Ticagrelor in Acute Coronary Syndromes: A Post Hoc Analysis of the Randomized GLOBAL LEADERS Trial.

JAMA cardiology, 2019
Importance The role of aspirin as part of antiplatelet regimens in acute coronary syndromes (ACS) needs to be clarified in the context of newer potent P2Y12 antagonists.
M. Tomaniak, P. Chichareon, Y. Onuma, E. Deliargyris, Kuniaki Takahashi, Norihiro Kogame, R. Modolo, Chun Chang, Tessa Rademaker-Havinga, R. Storey, G. Dangas, Deepak L. Bhatt, D. Angiolillo, C. Hamm, M. Valgimigli, S. Windecker, P. Steg, P. Vranckx, P. Serruys   +18 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Prerequisites for Affective Signal Processing (ASP) - Part V: A response to comments and suggestions [PDF]

, 2011
In four papers, a set of eleven prerequisites for affective signal processing (ASP) were identified (van den Broek et al., 2010): validation, triangulation, a physiology-driven approach, contributions of the signal processing community, identification of
Broek, Egon L. van den, Healey, Jennifer A., Janssen, Joris H., Westerink, Joyce H.D.M., Zwaag, Marjolein D. van der   +4 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Post Hoc Analysis of Life Expectancy in West Africa

American Journal of Applied Mathematics and Statistics, 2021
This paper investigates the effect of country, gender and the associated interaction term on life expectancy in West African countries. The empirical analysis revealed that country and gender have statistically significant effect on life expectancy in West Africa, while the associated interaction term has no significant effect on life expectancy.
openaire   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Unreported and Overlooked: A Post Hoc Analysis of COPD Symptom-Related Attacks from the RISE Study

International Journal of COPD, 2020
Gary T Ferguson,1 Tor Skärby,2 Lars H Nordenmark,2 Rosa Lamarca,3 Audrone Aksomaityte,4 Dan Lythgoe,4 Ileen Gilbert,5 Frank Trudo5 1Department of Medicine, Pulmonary Research Institute of Southeast Michigan, Farmington Hills, MI, USA ...
Ferguson GT, Skärby T, Nordenmark LH, Lamarca R, Aksomaityte A, Lythgoe D, Gilbert I, Trudo F   +7 more
doaj  

Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial

Intensive Care Medicine, 2018
PurposeThe EUPHRATES trial examined the impact of polymyxin B hemoperfusion (PMX) on mortality in patients with septic shock and endotoxemia, defined as EAA ≥ 0.60. No difference was found in 28-day all-cause mortality.
D. Klein, D. Foster, P. Walker, Sean M. Bagshaw, H. Mekonnen, Massimo Antonelli   +5 more
semanticscholar   +1 more source