Results 241 to 250 of about 2,152,009 (360)

Efficacy assessment of an active tau immunotherapy in Alzheimer’s disease patients with amyloid and tau pathology: a post hoc analysis of the “ADAMANT” randomised, placebo-controlled, double-blind, multi-centre, phase 2 clinical trialResearch in context

EBioMedicine
Summary: Background: Tau pathology correlates with and predicts clinical decline in Alzheimer’s disease. Approved tau-targeted therapies are not available.
Nicholas C. Cullen, Petr Novak, Duygu Tosun, Branislav Kovacech, Jozef Hanes, Eva Kontsekova, Michal Fresser, Stefan Ropele, Howard H. Feldman, Reinhold Schmidt, Bengt Winblad, Norbert Zilka   +11 more
doaj  

Effect of cariprazine on attention and quality of life in patients with predominant negative symptoms of schizophrenia: A post-hoc analysis. [PDF]

Schizophr Res Cogn
Oluboka OJ, Bardell A, Margolese HC, Tibbo PG, Buchy L, Di Cresce C, Yu J, McIntyre RS.   +7 more
europepmc   +1 more source

Metabolic Reprogramming of Cancer‐Associated Fibroblasts: Transforming Tumor Accomplices into Immunotherapeutic Allies

Advanced Functional Materials, Volume 35, Issue 13, March 25, 2025.
This study presents an FAP‐targeted LNP system designed to selectively target CAFs in CRPC. By inhibiting hexokinase 2 (HK2) and mitochondrial cytochrome c oxidase I (MTCO1), CAFs are reprogrammed from tumor‐promoting cells to immune‐supportive allies. This dual inhibition enhances T cell infiltration, suppresses angiogenesis, and improves the efficacy
Feng Qi, Dong Fu, Hongzhou Cai, Yuxiao Zheng, Ning Wang, Zicheng Xu   +5 more
wiley   +1 more source

Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial [PDF]

, 2015
Justin C. Brown, Kathryn H. Schmitz
openalex   +1 more source

Effect of Ozoralizumab Administration with or without Methotrexate in Patients with Rheumatoid Arthritis: A Post-Hoc Analysis. [PDF]

Rheumatol Ther
Tanaka Y, Horiuchi N, Sasajima C, Matsumoto R, Kawanishi M, Uchida S, Takeuchi T.   +6 more
europepmc   +1 more source

Dynamic Micromechanical Characterization of 3D Printed Bone In Vitro Models Manufactured via Vat Photopolymerization

Advanced Functional Materials, EarlyView.
This study presents a novel approach to designing and fabricating high‐porosity 3D‐printed scaffolds using a customized resin. Scaffold geometry, cellular interactions, and mechanical properties are analyzed to demonstrate these engineered bone models.
Sera Choi, Elizabeth Hunt, Edward A. Shangin, Zahra Bahranifard, Emma Nguyen, Caitlyn J. Collins, Abby R. Whittington   +6 more
wiley   +1 more source

Efficacy and Safety of Risedronate in Osteoporosis Subjects with Comorbid Diabetes, Hypertension, and/or Dyslipidemia: A Post Hoc Analysis of Phase III Trials Conducted in Japan [PDF]

, 2015
Daisuke Inoue, Ryoichi Muraoka, Ryo Okazaki, Yoshiki Nishizawà, Toshitsugu Sugimoto   +4 more
openalex   +1 more source

Hopeful for a second HOPE-2 post hoc analysis [PDF]

Nephrology Dialysis Transplantation, 2008
openaire   +2 more sources

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Tigecycline and Bacteremia—The Dangers of Post Hoc Analysis of Pooled Data [PDF]

Clinical Infectious Diseases, 2010
openaire   +3 more sources