Results 71 to 80 of about 6,663,865 (308)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Annual report : activities of the Legislative Post Audit Committee and the Legislative Division of Post Audit, fiscal year 1978.

, 1978
"A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; "December 22, 1978."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Biennial report : Legislative Post Audit Committee and the Legislative Division of Post Audit, fiscal years 1981 and 1982.

, 1982
"A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; "September 3, 1982.
Kansas. Legislative Post Audit Committee.
core  

Post‐normal conservation science fills the space between research, policy, and implementation

Conservation Science and Practice, 2019
The view that conservation is a linear exchange of knowledge between scientists and practitioners has led to the conceptualization of a “research‐implementation gap”.
Falko T. Buschke, Emily A. Botts, Samuel P. Sinclair   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Annual report : activities of the Legislative Post Audit Committee and the Legislative Division of Post Audit, fiscal year 1977.

, 1976
"A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; "December 20, 1977."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
core  

Implementation of Social Studies Learning at Cimahi City Junior High School Post-Covid-19 Pandemic

Forum Ilmu Sosial
This study aims to determine the implementation of social science learning at the end of the COVID-19 pandemic in junior high schools in Cimahi City. The approach used is qualitative with a descriptive method.
ARNIE FAJAR
doaj   +1 more source

ANALISIS FAKTOR PENDORONG REALISASI MANFAAT IMPLEMENTASI ERP DI PERUSAHAAN INDONESIA

J@ti Undip: Jurnal Teknik Industri, 2017
Pengelolaan implementasi ERP pada fase post project yaitu fase ketika ERP telah digunakan secara integral dalam perusahaan, menentukan terealisasinya manfaat dari implementasi ERP, karenanya terkait pengelolaan pada fase post project ini dibutuhkan ...
Iqbal Yulizar M., Rajesri Govindaraju
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source