Exploration, EarlyView.This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi +5 more
wiley +1 more source
Thrombotic Events in Patients With Paroxysmal Nocturnal Haemoglobinuria Using Eculizumab: A Post-Marketing Surveillance Sub-Analysis. [PDF]
EJHaemIkezoe T +4 more
europepmc +1 more source
Post‐marketing surveillance [letter] [PDF]
British Journal of Clinical Pharmacology, 1988 openaire +2 more sources
Exploration, EarlyView.A PD‐L1 nanobody‐engineered synthetic RNA virus (αPDL1‐VLPs/shPCSK9) is fabricated to inhibit PCSK9 and upregulate MHC‐I to facilitate T cells recognition of hepatocellular carcinoma (HCC). Moreover, αPDL1‐VLPs/shPCSK9 can recognize PD‐L1 and block the PD‐1/PD‐L1 pathway to prevent immune evasion, while promoting M2‐to‐M1 macrophages polarization ...
Chuyu Huang +9 more
wiley +1 more source
Post-Marketing Surveillance of Adverse Events Following 23-Valent Pneumococcal Polysaccharide Vaccination - China, 2021-2024. [PDF]
China CDC WklyLi Y +9 more
europepmc +1 more source
Vehicle Fires: Significant Fire Hazard in Transportation Infrastructure
Fire and Materials, EarlyView.ABSTRACT Vehicle flammability poses a critical threat to transportation infrastructure, with recent fires in depots, tunnels, and car parks highlighting systemic vulnerabilities. These incidents often result in the total loss of vehicles and buildings, revealing the inadequacy of current fire safety standards for vehicle materials.
Anja Hofmann‐Böllinghaus +2 more
wiley +1 more source
Real-world safety and effectiveness of nivolumab in patients with cancer of unknown primary: results from a nationwide post-marketing surveillance in Japan. [PDF]
Int J Clin OncolKawasaki A +4 more
europepmc +1 more source
Colonial and gendered peace: Decolonial perspectives on peace in Nagorno‐Karabakh
Feminist Anthropology, EarlyView.Abstract This article critically interrogates peace processes in the aftermath of the First Nagorno‐Karabakh War by centering the lived experiences and political voices of Armenian and Azerbaijani internally displaced and refugee women, based on ethnographic fieldwork and in‐depth interviews conducted in 2019.
Ramil Zamanov
wiley +1 more source
Darbepoetin alfa for the treatment of anemia in myelodysplastic syndromes: a post-marketing surveillance study in Japan. [PDF]
Int J HematolMorita Y, Tsuji Y, Yasukawa T, Mitani K.
europepmc +1 more source
Feminist Anthropology, EarlyView.Abstract In this paper, we will construct and analyze intersecting definitions of womanhood among middle‐class women living in Karachi, Pakistan. Women are agents of their lives and are not passive voices. In this paper, we present narratives of women who resist “societal” narratives of womanhood to live a life of their choosing.
Urooba Ahmed Fatima +7 more
wiley +1 more source