Results 31 to 40 of about 4,915,541 (300)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 1991 Die Maurmer Post erschien von 1975 bis 1994 wöchentlich als eigenständige Rubrik mit eigener Redaktion im Anzeiger von Uster bzw.
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 2012 This blog will collect my research notes on texts that deal with social theory, modernity, and art. I will focus on spaces, objects and representations that deal with modernity.
Pablo Markin
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Marseille, une ville méditerranéenne entre pénurie et inondation
VertigO, 2011 Based on a interdisciplinary analyse crossing history and sociology, this paper analyses the relationship to water of the inhabitants and the decision makers of the Mediterranean French city of Marseilles, from the XIXth century to nowadays.
Martine Chalvet, Cécilia Claeys
doaj +1 more source
The post-modern research system [PDF]
Science and Public Policy, 1996 The landscape of science is changing radically. In particular, there is increasing heterogeneity of actors, research sites, knowledge and networks. Science policy-makers have to respond to these changes, but heterogeneity makes it more difficult to impose own goals on the research system.
Arie Rip, Barend J R van der Meulen
openaire +3 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
, 1980 "A Report to the Kansas Legislature by the Legislative Post Audit Committee, state of Kansas."; "December 1, 1980."Constitutes the annual report of the ...
Kansas. Legislative Post Audit Committee.
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Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source