The Distribution of opiates, cocaine and their metabolites in skeletal muscle tissue and vitreous humour as an aid to post-mortem toxicological interpretation. [PDF]
Post-mortem blood drug concentrations vary greatly and as a consequence of post-mortem change and redistribution may not reflect the concentration at the time of death.
Rees, Kelly-Ann
core +9 more sources
Exploring the role of mu opioid receptor (OPRM1) and CYP2B6 gene variations for methadone pharmacogenomics. Can these variations be used to advance toxicological interpretation post-mortem?. [PDF]
Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid ...
Bunten, Hannah
core +9 more sources
Forensic Biochemical Markers to Evaluate the Agonal Period: A Literature Review
Molecules, 2021 Currently, forensic research is multidisciplinary with new methods and parameters useful to define the cause and time of death as well as survival/agony times.
Enrica Rosato +6 more
doaj +1 more source
Profiling of RNA degradation for estimation of post mortem [corrected] interval. [PDF]
PLoS ONE, 2013 An estimation of the post mortem interval (PMI) is frequently touted as the Holy Grail of forensic pathology. During the first hours after death, PMI estimation is dependent on the rate of physical observable modifications including algor, rigor and ...
Fernanda Sampaio-Silva +4 more
doaj +1 more source
MicroRNAs as Useful Tools to Estimate Time Since Death. A Systematic Review of Current Literature
Diagnostics, 2021 Estimating the time of death remains the most challenging question in forensic medicine, because post-mortem interval (PMI) estimation can be a remarkably difficult goal to achieve. The aim of this review is to analyze the potential of microRNAs (miRNAs)
Aniello Maiese +7 more
doaj +1 more source
Diagnostics, 2021 (1) Background: The estimation of the post mortem interval (PMI) is a challenge for forensic pathologists because data emerging from methods commonly applied are not always conclusive, since several conditions exist that may affect the reliability of ...
Cristina Mondello +10 more
doaj +1 more source
Insects, 2021 Establishing the post mortem interval (PMI) is a key component of every medicolegal death investigation. Several methods based on different approaches have been suggested to perform this estimation.
Lorenzo Franceschetti +5 more
doaj +1 more source
Dysregulation of miR-381-3p and miR-23b-3p in skeletal muscle could be a possible estimator of early post-mortem interval in rats [PDF]
PeerJ, 2021 Background The post-mortem interval (PMI) is the time elapsed since the dead of an individual until the body is found, which is relevant for forensic purposes. The miRNAs regulate the expression of some genes; and due to their small size, they can better
Vanessa Martínez-Rivera +11 more
doaj +2 more sources
Looking for Post-Mortem Metabolomic Standardization: Waiting for Godot—The Importance of Post-Mortem Interval in Forensic Metabolomics [PDF]
Chemical Research in Toxicology, 2021 A growing body of evidence suggests that the post-mortem interval exerts a strong effect on the metabolome, independently of the biological matrix or the cause of death. A sound and shared approach in standardization is mandatory.
Chighine, Alberto +3 more
openaire +3 more sources
Importance of entomology in veterinary forensics [PDF]
Veterinarski Glasnik, 2008 Entomological evidence is legal evidence in the form of insects or related artropodes, and a field of their study in the aim of medicocriminal applications and veterinary-medical forensic cases is forensic entomology.
Aleksić Jelena, Jović Slavoljub
doaj +1 more source