Results 81 to 90 of about 93,052 (247)

Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Novel stent technologies offer early intravascular treatment options for coarctation (COA). Mid‐to‐long‐term cardiovascular responses to early COA stent interventions are undefined. Aims We studied a porcine model of COA, with and without early stent implantation with serial dilation to adult aortic diameters, aiming to define ...
Leah M. Gober, Michael A. Stellon, Matt A. Culver, Amy Frenkel, Dana Irrer, Colleen M. Witzenburg, Alejandro Roldán‐Alzate, Luke Lamers   +7 more
wiley   +1 more source

Social Autopsy is a dire need for investigating child mortality in Pakistan

International Journal of Endorsing Health Science Research, 2016
The world has been unable to meet the United Nations Millennium Development Goals (MDGs) of reducing child mortality by 2015. Since 1990, there is an established disparity of under-5 mortality rates among countries across the globe. This disparity is due
Muhammad Bilal Siddiqui, Chiu Wan Ng, Wah Yun Low   +2 more
doaj   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Predictors of post-anaesthetic mortality in newborns in Kinshasa (2025-2026): a prospective cohort study. Original article. [PDF]

Pediatric Anesthesia and Critical Care Journal (PACCJ)
ntroduction Mortality in neonatal anaesthesia is low in high-income countries (
D. Mwela, B.K. Nkongolo, S. Ndjoko, P. Mukuna, W. Mbombo, T. Mawisa, J. Kalambay, JJ. Kalongo, L. Okenge, B. Barhayiga, J. Nsiala   +10 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Effectiveness of 4% chlorhexidine umbilical cord care on neonatal mortality in Southern Province, Zambia (ZamCAT): a cluster-randomised controlled trial

The Lancet Global Health, 2016
Background: Chlorhexidine umbilical cord washes reduce neonatal mortality in south Asian populations with high neonatal mortality rates and predominantly home-based deliveries.
Katherine E A Semrau, PhD, Julie Herlihy, MD, Caroline Grogan, MSc, Kebby Musokotwane, MD, Kojo Yeboah-Antwi, MBChB, Reuben Mbewe, MMed, Bowen Banda, MDM, Chipo Mpamba, DipDM, Fern Hamomba, ZRM, Portipher Pilingana, BSc, Andisen Zulu, BA, Pascalina Chanda-Kapata, PhD, Godfrey Biemba, MBChB, Prof. Donald M Thea, MD, William B MacLeod, ScD, Prof. Jonathon L Simon, DSc, Prof. Davidson H Hamer, MD   +16 more
doaj   +1 more source

Inter‐rater reliability and clinical utility of the BASED score in infantile epileptic spasms syndrome

Epileptic Disorders, EarlyView.
Abstract Objective Hypsarrhythmia is the classical EEG pattern of children with infantile epileptic spasms syndrome (IESS). Multifocal spikes, slow waves of large amplitude, and chaoticity are its main characteristics, but these lack clear definitions, and the interrater reliability (IRR) is poor.
T. P. Cramer, B. Johnsen, V. S. Hansen, E. Qerama, T. S. Engedal   +4 more
wiley   +1 more source

What was Killing Babies in 19th-Century Europe? Categorising Their Deaths Using ICD10h

Historical Life Course Studies
This paper draws together the results from a set of complementary analyses of the causes of infant mortality in eight European port cities in the late 19th century.
Alice Reid, Angélique Janssens
doaj   +1 more source

Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality

Acta Biomedica Scientifica, 2017
Aim: to establish a link between the level of folic acid, vitamin D and iodine consumption, and infant and perinatal mortality, morbidity of childhood tuberculosis in the Irkutsk region.
L. A. Reshetnik, T. A. Spasich, T. V. Boyko, M. V. Grigorieva, I. Y. Kozlovskaya   +4 more
doaj   +1 more source