Results 41 to 50 of about 4,926,639 (167)

Advancing Treatment of Degenerative Eye Diseases at the Nanoscale

open access: yesSmart Medicine, Volume 5, Issue 4, August 2026.
Nanotherapeutics possess the potential to overcome longstanding bottlenecks in treating degenerative ophthalmic diseases. With a highly tunable surface chemistry, nanotechnology platforms can be customized to navigate specific anatomical barriers in the eye and target pathways of diseases.
Li Yao Jin   +5 more
wiley   +1 more source

Graft Survival after Penetrating Keratoplasty in Cases of Trabeculectomy versus Ahmed Valve Implant

open access: yesJournal of Ophthalmology, 2018
Purpose. To compare the corneal graft survival rates after penetrating keratoplasty (PKP) in cases of post-PKP glaucoma managed by either trabeculectomy with mitomycin C or Ahmed glaucoma valve (AGV). Methods.
Abdelhamid Elhofi, Hany Ahmed Helaly
doaj   +1 more source

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

open access: yesActa Ophthalmologica, Volume 104, Issue 5, Page e516-e529, August 2026.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg   +6 more
wiley   +1 more source

Glaucoma after Penetrating Keratoplasty: Incidence, Risk Factors, and Management [PDF]

open access: yes, 2011
Purpose. To report the incidence and risk factors for postkeratoplasty glaucoma (PKG), as well as its management. Subjects and Methods. 122 eyes, (43% with pseudophakic and aphakic bullous keratopathy (PABK)) which underwent penetrating keratoplasty (PK),
Ahmet Ozer   +4 more
core   +1 more source

Repeat keratoplasty in failed Descemet stripping automated endothelial keratoplasty

open access: yesIndian Journal of Ophthalmology, 2019
Purpose: To evaluate the clinical factors associated with repeat Descemet stripping automated endothelial keratoplasty (DSAEK) or penetrating keratoplasty (PKP) in cases of failed DSAEK.
Manpreet Kaur   +6 more
doaj   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

open access: yesAdvanced Science, Volume 13, Issue 41, 22 July 2026.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao   +10 more
wiley   +1 more source

Graft Failure and Repeat Penetrating Keratoplasty

open access: yes, 2021
Objectives: in this study, we report the indications and outcomes of repeat penetrating keratoplasty and the reasons for graft failure. Materials and Methods: We performed a retrospective data analysis of patients who had undergone 2 or more penetrating ...
Selver, Ozlem Barut   +4 more
core   +1 more source

Medium term results of penetrating keratoplasty [PDF]

open access: yes, 2015
Purpose: This is a retrospective evaluation of penetrating keratoplasty for optical purpose in the Eye Clinic of the Clinical Emergency Hospital "St. Spiridon "Iasi. Methods: The study evaluated 51 eyes of 50 patients, mean age of patients was 50.8 years.
Chiselita, Dorin   +3 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Deep anterior lamellar keratoplasty versus penetrating keratoplasty: comparison of clinical outcomes in contralateral eyes

open access: yes, 2022
Purpose: This study aimed to compare the clinical outcomes following deep anterior lamellar keratoplasty and penetrating keratoplasty in contralateral eyes of the same patients.
Nesrin Tutaş Günaydın (12490533)   +2 more
core   +1 more source

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